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Updated: Jul 6, 2026

High-resolution Structural Magnetic Resonance Imaging of the Human Subcortex In Vivo and Postmortem
Published on: December 30, 2015
SCIWORA in MRI era
Kemal Yucesoy1, K Zafer Yuksel
1Department of Neurosurgery, Faculty of Medicine, Dokuz Eylul University, Izmir, Turkey.
Abstract:
The aim of this report is to discuss the use of the term 'Spinal Cord Injury Without Radiographic Abnormality' (SCIWORA) in the medical literature ever since MRI became commonly employed in the diagnosis of spinal cord injuries. Using the PubMed database and the keywords 'SCIWORA and MRI', we found 30 published articles in the English-language literature. Incidence, clinical and radiological data, and MRI findings were evaluated in all articles, which included one meta-analysis, two reviews, 10 case series, and 17 case reports. The incidence of SCIWORA among children was found to be between 3.3% and 32.0%. This wide range was directly related to patients' age, authors' specialty, and utilization of MRI. After MRI became commonly used for spinal injuries, the term has taken on an ambiguous meaning in the literature. In our opinion, if any pathology is detected on MRI with or without radiographic abnormality, the patients should not be classed, as SCIWORA and 'real-SCIWORA' should be determined as 'Spinal Cord Injury Without Neuroimaging Abnormality' in cases with normal MRI.
Insights
The term Spinal Cord Injury Without Radiographic Abnormality (SCIWORA) is ambiguous since MRI use. Researchers propose renaming it Spinal Cord Injury Without Neuroimaging Abnormality for clarity.
Area of Science:
- Neurology
- Radiology
- Medical Imaging
Background:
- The term Spinal Cord Injury Without Radiographic Abnormality (SCIWORA) has been used in medical literature.
- The advent of Magnetic Resonance Imaging (MRI) has complicated the definition and application of SCIWORA.
Purpose of the Study:
- To analyze the usage and implications of the term SCIWORA in the context of modern neuroimaging.
- To propose a revised definition for SCIWORA to improve diagnostic clarity.
Main Methods:
- A literature search was conducted on PubMed using keywords 'SCIWORA and MRI'.
- 30 relevant English-language articles were reviewed, including meta-analyses, reviews, case series, and case reports.
- Data on incidence, clinical presentation, radiological findings, and MRI results were evaluated.
Main Results:
- The incidence of SCIWORA in children varied widely (3.3%–32.0%), influenced by patient age, author specialty, and MRI utilization.
- The widespread use of MRI has led to an ambiguous interpretation of SCIWORA in published studies.
- A significant proportion of cases previously labeled SCIWORA may show abnormalities on MRI.
Conclusions:
- The current definition of SCIWORA is problematic due to the sensitivity of MRI in detecting spinal cord abnormalities.
- It is recommended to redefine SCIWORA as 'Spinal Cord Injury Without Neuroimaging Abnormality' for cases with completely normal MRI findings.
- This redefinition aims to reserve the term for injuries with no detectable abnormalities on advanced imaging, enhancing diagnostic precision.
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