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Updated: Jul 6, 2026

11:08
Chemo-enzymatic Synthesis of N-glycans for Array Development and HIV Antibody Profiling
Published on: February 5, 2018
Synthesis, anti-HIV-1 activity, and modeling studies of N-3 Boc TSAO compound
Cyrille Tomassi1, Van Nhien Albert Nguyen, José Marco-Contelles
1Laboratoire des Glucides (UMR6219), Université de Picardie Jules Verne, 33 rue Saint Leu, 80039 Amiens, France.
Bioorganic & Medicinal Chemistry Letters
|March 21, 2008
Abstract:
The synthesis and the biological evaluation of the anti-HIV-1 activity of TSAO-Boc(3)T (8) are described. The computational analysis showed that the N-3 Boc group promotes new interactions in the binding site of the enzyme leading to a good inhibitory activity.

