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Updated: Jul 6, 2026

Non-Invasive Compression-Induced Anterior Cruciate Ligament (ACL) Injury and In Vivo Imaging of Protease Activity in Mice
Published on: September 29, 2023
Bone bruises associated with ACL rupture: correlation with injury mechanism
Darius G Viskontas1, Bruno M Giuffre, Naven Duggal
1Department of Orthopaedic Surgery, Royal Columbian Hospital, 330 East Columbia St, New Westminster, BC, Canada.
Background:
Different patterns of bone bruising are seen on magnetic resonance imaging in acute anterior cruciate ligament ruptures. These patterns may relate to the mechanism of injury.
Hypothesis:
There is a correlation between the mechanism of anterior cruciate ligament injury and bone bruise patterns on magnetic resonance imaging.
Study Design:
Cohort study; Level of evidence, 2.
Methods:
Data regarding the mechanism of anterior cruciate ligament rupture were collected prospectively on patients who had anterior cruciate ligament reconstructions. Inclusion criteria included a clear history of mechanism, magnetic resonance imaging within 6 weeks of injury, and no previous knee injury. Patients were divided into noncontact and contact mechanism groups. Bone bruise frequency, location, depth, and intensity were analyzed using magnetic resonance imaging and correlated with the mechanism of injury.
Results:
Two hundred fifty-six patients were identified; 100 met the inclusion criteria, 86 were in the noncontact mechanism group, and 14 were in the contact mechanism group. The proportion of bone bruises in the lateral compartment in both groups was higher (P < .001) than in the medial compartment. Bone bruising was more frequent, deeper, and more intense in the noncontact group, with frequency (P = .019) and intensity (P < .001) scores reaching significance at the lateral tibial plateau. Medial compartment bone bruising was seen more frequently than previously reported, particularly in the noncontact group.
Conclusion:
The noncontact mechanism appears to cause more severe bone bruising in both the medial and lateral compartments.
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