Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

EDTA: Auxiliary Complexing Reagents01:26

EDTA: Auxiliary Complexing Reagents

EDTA titrations are usually carried out in highly basic conditions, where the fully deprotonated form of EDTA, Y4−, actively complexes with the free metal ions in the solution. Several metal ions precipitate as hydrous oxide (hydroxides, oxides, or oxyhydroxides) under these conditions, lowering the concentration of free metal ions in the solution. For this reason, auxiliary complexing agents or ligands such as ammonia, tartrate, citrate, or triethanolamine are used in EDTA titrations to...
Complexometric Titration: Ligands00:43

Complexometric Titration: Ligands

Different monodentate and polydentate ligands are used as complexing agents in complexometric titration reactions. The formation of complexes by mono- and bidentate ligands involves two or more intermediate steps, limiting their use as complexing agents. In comparison, polydentate ligands can form complexes with metal ions in a single-step process, facilitating sharper end points. This means polydentate ligands, such as amino carboxylic acid derivatives, are most commonly employed in...
EDTA: Chemistry and Properties01:22

EDTA: Chemistry and Properties

Polydentate ligands are most widely used in complexometric titrations because they form more stable complexes with the metal ions than mono- or bidentate ligands due to the chelate effect. Examples of polydentate ligands are ethylenediaminetetraacetic acid (EDTA), crown ethers, and cryptands. The most important feature of optimal polydentate ligands is the ability to form 1:1 complexes in a single-step process. Amino carboxylic acid derivatives are frequently used as complexing agents. EDTA is...
Crystal Field Theory - Tetrahedral and Square Planar Complexes02:46

Crystal Field Theory - Tetrahedral and Square Planar Complexes

Tetrahedral Complexes
Crystal field theory (CFT) is applicable to molecules in geometries other than octahedral. In octahedral complexes, the lobes of the dx2−y2 and dz2 orbitals point directly at the ligands. For tetrahedral complexes, the d orbitals remain in place, but with only four ligands located between the axes. None of the orbitals points directly at the tetrahedral ligands. However, the dx2−y2 and dz2 orbitals (along the Cartesian axes) overlap with the ligands less than the dxy,...
Ladder Diagrams: Complexation Equilibria01:07

Ladder Diagrams: Complexation Equilibria

Ladder diagrams are useful for evaluating equilibria involving metal-ligand complexes. The vertical scale of the ladder diagram represents the concentration of unreacted or free ligand, pL. The horizontal lines on the scale depict the log of stepwise formation constants for metal-ligand complexes and indicate the dominant species in all the regions.
The formation constant, K1, for the formation of Cd(NH3)2+ complex from cadmium and ammonia is 3.55 × 102. Log K1 (i.e. pNH3) is 2.55, and...
Complexation Equilibria: The Chelate Effect01:19

Complexation Equilibria: The Chelate Effect

In complexation reactions, metal atoms or cations interact with ligands to form donor-acceptor adducts called metal complexes. Ligands that bind through one donor site are monodentate, ligands with two donor sites are bidentate, and those with more than two donor sites are polydentate ligands. For example, ethylene diamine is a bidentate ligand that binds through two nitrogen donor atoms, forming a five-membered ring. EDTA is a polydentate ligand that binds through four oxygen and two nitrogen...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

PPTMP: An Asymmetric Tetradentate Ligand for Trivalent Lanthanide/Actinide Separation in Nuclear Waste Management.

Inorganic chemistry·2026
Same author

Contrasting single-molecule magnet behaviour in dysprosium and terbium bis(stannolediide) complexes.

Nature chemistry·2026
Same author

Toward Understanding Prolate 4f Monomers: Numerical Predictions and Experimental Validation of Electronic Properties and Slow Relaxation in a Muffin-Shaped Er<sup>III</sup> Complex.

Inorganic chemistry·2026
Same author

Distinct Ligand- and Metal-Centered Phosphorescence in a Terbium Carbazolyl Complex.

Chemistry (Weinheim an der Bergstrasse, Germany)·2025
Same author

Ultrabroadband 1D and 2D NMR Spectroscopy.

Angewandte Chemie (International ed. in English)·2025
Same author

Pure Molecular Inorganic Rings: Mixed Group 14/15 Metallacycles.

Angewandte Chemie (International ed. in English)·2025
Same journal

Ligand non-innocence enables HAT at dinuclear nickel complexes.

Dalton transactions (Cambridge, England : 2003)·2026
Same journal

Preservation of the 2<i>H</i>-MoS<sub>2</sub> structure in intercalation compounds with bulky cations.

Dalton transactions (Cambridge, England : 2003)·2026
Same journal

A "one-stone-two-birds" strategy for enhancing the quantum yield and designing dual-emission AIE MOFs.

Dalton transactions (Cambridge, England : 2003)·2026
Same journal

Scalable synthesis of highly crystalline 2D bimetallic MOFs on GO as electrode materials for alkaline zinc batteries.

Dalton transactions (Cambridge, England : 2003)·2026
Same journal

Catalytic surface degradation of (CF<sub>2</sub>H)<sub>2</sub>O to CF<sub>3</sub>H at a Si-teflate doped aluminium chlorofluoride Lewis superacid.

Dalton transactions (Cambridge, England : 2003)·2026
Same journal

A molecular 'LEGO®' approach to high-spin triangular {Mn<sup>III</sup>Ln<sub>2</sub>} clusters from {Mn<sup>III</sup>} and {Ln<sub>2</sub>} metalloligands.

Dalton transactions (Cambridge, England : 2003)·2026
See all related articles

Related Experiment Video

Updated: Jul 6, 2026

Thermochemical Studies of Ni(II) and Zn(II) Ternary Complexes Using Ion Mobility-Mass Spectrometry
16:11

Thermochemical Studies of Ni(II) and Zn(II) Ternary Complexes Using Ion Mobility-Mass Spectrometry

Published on: June 8, 2022

TADDOLate complexes of zinc.

Simmi Datta1, Michael T Gamer, Peter W Roesky

  • 1Institut für Chemie und Biochemie, Freie Universität Berlin, Fabeckstrasse 34-36, 14195, Berlin, Germany.

Dalton Transactions (Cambridge, England : 2003)
|March 21, 2008
PubMed
Summary
This summary is machine-generated.

Researchers synthesized novel zinc complexes using TADDOL (alpha,alpha,alpha

More Related Videos

Characterizing Mammalian Zinc Transporters Using an In Vitro Zinc Transport Assay
07:55

Characterizing Mammalian Zinc Transporters Using an In Vitro Zinc Transport Assay

Published on: June 2, 2023

Ion Mobility-Mass Spectrometry Techniques for Determining the Structure and Mechanisms of Metal Ion Recognition and Redox Activity of Metal Binding Oligopeptides
11:04

Ion Mobility-Mass Spectrometry Techniques for Determining the Structure and Mechanisms of Metal Ion Recognition and Redox Activity of Metal Binding Oligopeptides

Published on: September 7, 2019

Related Experiment Videos

Last Updated: Jul 6, 2026

Thermochemical Studies of Ni(II) and Zn(II) Ternary Complexes Using Ion Mobility-Mass Spectrometry
16:11

Thermochemical Studies of Ni(II) and Zn(II) Ternary Complexes Using Ion Mobility-Mass Spectrometry

Published on: June 8, 2022

Characterizing Mammalian Zinc Transporters Using an In Vitro Zinc Transport Assay
07:55

Characterizing Mammalian Zinc Transporters Using an In Vitro Zinc Transport Assay

Published on: June 2, 2023

Ion Mobility-Mass Spectrometry Techniques for Determining the Structure and Mechanisms of Metal Ion Recognition and Redox Activity of Metal Binding Oligopeptides
11:04

Ion Mobility-Mass Spectrometry Techniques for Determining the Structure and Mechanisms of Metal Ion Recognition and Redox Activity of Metal Binding Oligopeptides

Published on: September 7, 2019

Area of Science:

  • Organometallic Chemistry
  • Coordination Chemistry
  • Chiral Synthesis

Background:

  • TADDOL (alpha,alpha,alpha',alpha'-Tetraaryl-2,2-dimethyl-1,3-dioxolane-4,5-dimethanol) derivatives are established chiral auxiliaries in transition metal-mediated enantioselective synthesis.
  • The coordination chemistry of TADDOLates with zinc has not been previously explored.

Purpose of the Study:

  • To report the synthesis and structural characterization of novel zinc-TADDOLate complexes.
  • To investigate the coordination behavior of TADDOLate ligands with zinc.

Main Methods:

  • Synthesis of a homo trinuclear zinc complex, [Me2Zn3{(S,S)-TADDOLate}2(THF)2], via reaction of TADDOL with dimethylzinc.
  • Synthesis of a hetero trinuclear complex, [Li2Zn{(S,S)-TADDOLate}2(THF)2], from dilithium TADDOLate and zinc dichloride.
  • Structural characterization of the synthesized complexes.

Main Results:

  • Successful synthesis of both homo and hetero trinuclear zinc-TADDOLate complexes.
  • Structural elucidation revealed a non-linear M...Zn...M trimetallic arrangement in both complexes.
  • The trimetallic core is effectively shielded by two TADDOLate ligands.

Conclusions:

  • This study presents the first synthesis and structural characterization of zinc-TADDOLate complexes.
  • The TADDOLate ligand can effectively coordinate with zinc to form unique trimetallic structures.
  • These findings expand the scope of TADDOLate chemistry and may offer new chiral ligands for catalysis.