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Covalent Attachment of Single Molecules for AFM-based Force Spectroscopy
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Chemical modifications of AFM tips for the study of molecular recognition events

Régis Barattin1, Normand Voyer

  • 1CEA-LETI, Laboratoire de Fonctionnalisation et Chimie pour les Microsystèmes, 17 rue des Martyrs, F-38054 Grenoble cedex 9, France.

Chemical Communications (Cambridge, England)
|March 21, 2008
PubMed

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Atomic Force Microscopy01:08

Atomic Force Microscopy

Atomic force microscopy (AFM) is a type of scanning probe microscopy that can analyze topographic details of various specimens like ceramics, glass, polymers, and biological samples. AFM offers over 1000 times more resolution than the optical imaging system. Images generated from AFM are three-dimensional surface profiles, offering an advantage over the flat, two-dimensional images from other imaging techniques.
The AFM Probe
The probe is regarded as the heart of any AFM setup and comprises the...