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Related Concept Videos

Psychoneuroimmunology: Cardiovascular Disease01:27

Psychoneuroimmunology: Cardiovascular Disease

Psychoneuroimmunology (PNI) is a multidisciplinary field that examines how psychological factors, particularly stress, interact with the immune system and impact physical health. Research in PNI has shown that chronic or traumatic stress can disrupt both the hypothalamic-pituitary-adrenal axis and the sympathetic nervous system. These disruptions contribute to serious health conditions, including cardiovascular diseases.
A key area of focus in PNI is the relationship between stress and coronary...
Psychoneuroimmunology: Diabetes and Cancer01:19

Psychoneuroimmunology: Diabetes and Cancer

Chronic stress has been linked to both the onset and progression of serious health conditions, including Type 2 diabetes and cancer. Type 2 diabetes, a widespread chronic illness, is closely associated with obesity and insulin resistance, both of which often worsen under stress. Studies indicate that men experiencing high levels of chronic stress face a 45% higher risk of developing diabetes compared to those with minimal stress. Stress triggers physiological responses that elevate blood...
Psychological Responses to Stress01:20

Psychological Responses to Stress

Psychological responses to stress encompass the various cognitive and emotional reactions individuals experience when faced with challenging or threatening situations, such as a job loss. Prolonged exposure to stressors can disturb emotional balance, increasing negative emotions (e.g., anxiety and sadness) and diminishing positive emotions (e.g., joy and satisfaction). These persistent emotional shifts are associated with an increased risk of both physical illness and mental health issues, such...
Introduction to Stress and Lifestyle01:27

Introduction to Stress and Lifestyle

Stress is a multifaceted response to events perceived as challenging or threatening, highlighting physical, emotional, cognitive, and behavioral reactions. Physically, stress can lead to fatigue, sleep disruptions, and various health issues such as frequent colds, chest pains, and nausea. Emotionally, it can manifest as anxiety, depression, irritability, and anger triggered by both minor and major life events. Cognitively, it may result in difficulty in concentration, memory, and...
Physiological Foundation of Stress01:24

Physiological Foundation of Stress

Stress triggers a coordinated physiological response involving the sympathetic nervous system (SNS) and the hypothalamic-pituitary-adrenal (HPA) axis. This dual activation ensures that the body is prepared for both immediate and prolonged stress management. The process begins with the perception of a stressor. This initial phase activates the SNS, leading to the rapid release of adrenaline (epinephrine) from the adrenal glands.
Role of the Sympathetic Nervous System
Adrenaline triggers the...
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Stress and Mental Health

Chronic stress profoundly affects mental health, significantly influencing mood, behavior, and overall quality of life. Research closely links chronic stress with mental health conditions such as depression, anxiety, and substance use disorders. Ongoing exposure to stress can lead to physiological and psychological changes, initiating a cycle of emotional distress and maladaptive coping mechanisms.
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Related Experiment Video

Updated: Jul 6, 2026

Measuring Psoriasis Severity at Home
02:28

Measuring Psoriasis Severity at Home

Published on: March 1, 2024

Psoriasis and stress: a prospective study.

M Berg1, M Svensson, M Brandberg

  • 1Department of Dermatology, University Hospital, Uppsala, Sweden. mats.berg@akademiska.se

Journal of the European Academy of Dermatology and Venereology : JEADV
|March 22, 2008
PubMed
Summary
This summary is machine-generated.

This study found no clear link between stress and psoriasis flare-ups in nine women. The results do not support the common belief that stress worsens psoriasis symptoms.

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The Trier Social Stress Test Protocol for Inducing Psychological Stress
09:39

The Trier Social Stress Test Protocol for Inducing Psychological Stress

Published on: October 19, 2011

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Last Updated: Jul 6, 2026

Measuring Psoriasis Severity at Home
02:28

Measuring Psoriasis Severity at Home

Published on: March 1, 2024

The Trier Social Stress Test Protocol for Inducing Psychological Stress
09:39

The Trier Social Stress Test Protocol for Inducing Psychological Stress

Published on: October 19, 2011

Area of Science:

  • Dermatology
  • Psychoneuroimmunology
  • Clinical Research

Background:

  • Psoriasis is commonly believed to be exacerbated by stress.
  • Previous evidence is largely based on retrospective self-reported data.
  • Controlled prospective studies investigating this link are lacking.

Purpose of the Study:

  • To prospectively investigate the relationship between stress and psoriasis exacerbation.
  • To determine if stress is a significant worsening factor in plaque psoriasis.

Main Methods:

  • A prospective study involving nine women with moderate plaque psoriasis.
  • Daily diaries tracked stress levels and psoriasis severity.
  • Psoriasis Area and Severity Index (PASI) scores and stress-related blood samples were collected.

Main Results:

  • No consistent pattern was observed between stress levels and psoriasis worsening in the majority of patients.
  • Some patients showed no temporal relationship between stress and psoriasis onset.
  • Two patients experienced elevated stress levels after psoriasis outbreaks.

Conclusions:

  • This small-scale study does not provide evidence to support stress as a direct worsening factor for psoriasis.
  • Further research with larger cohorts may be needed to fully elucidate the stress-psoriasis connection.