Related Experiment Video
Updated: Jul 6, 2026

Drug Repurposing Hypothesis Generation Using the "RE:fine Drugs" System
Published on: December 11, 2016
Does reimportation reduce price differences for prescription drugs? Lessons from the European Union
Margaret K Kyle1, Jennifer S Allsbrook, Kevin A Schulman
1The Fucqua School of Business, Duke University, Durham, NC, USA.
Objective:
To examine the effect of parallel trade on patterns of price dispersion for prescription drugs in the European Union.
Data Sources:
Longitudinal data from an IMS Midas database of prices and units sold for drugs in 36 categories in 30 countries from 1993 through 2004.
Study Design:
The main outcome measures were mean price differentials and other measures of price dispersion within European Union countries compared with within non-European Union countries.
Data Collection/Extraction Methods:
We identified drugs subject to parallel trade using information provided by IMS and by checking membership lists of parallel import trade associations and lists of approved parallel imports.
Principal Findings:
Parallel trade was not associated with substantial reductions in price dispersion in European Union countries. In descriptive and regression analyses, about half of the price differentials exceeded 50 percent in both European Union and non-European Union countries over time, and price distributions among European Union countries did not show a dramatic change concurrent with the adoption of parallel trade. In regression analysis, we found that although price differentials decreased after 1995 in most countries, they decreased less in the European Union than elsewhere.
Conclusions:
Parallel trade for prescription drugs does not automatically reduce international price differences. Future research should explore how other regulatory schemes might lead to different results elsewhere.
Related Concept Videos
Pharmaceutical Alternatives: Excipients and Impurities-Related Therapeutic Nonequivalence
Pharmaceutical Alternatives: Stability-Related Therapeutic Nonequivalence
Prescription, Nonprescription and Orphan Drugs
The misuse and addiction to prescription drugs is a growing problem that can affect people of all age groups, specifically teenagers. This can happen when prescription medications are used in ways not intended by the prescriber, such as taking someone else's prescription or using medication for...
Drug Products: Biologics, Biosimilars and Interchangeables
Bioequivalence: Overview
Drug Control Governance: Regulatory Bodies and Their Impact

