Related Experiment Video
Updated: Jul 6, 2026

04:23
Application of Hemostatic Devices in Laparoscopic Hepatectomy
Published on: April 19, 2022
Use of FloSeal haemostatic gel in massive obstetric haemorrhage: a case report
K T Moriarty1, S Premila, P J Bulmer
1Children's and Women's Services, St George's Healthcare NHS Trust, London, UK. estherandtim@yahoo.co.uk
Abstract
No abstract available in PubMed .
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Introduction to Hemostasis
Hemostasis is a complex physiological process that prevents excessive bleeding when a blood vessel is injured. It's crucial for maintaining the integrity of the circulatory system, as it ensures that our blood remains fluid while still within the vascular network and yet clots to prevent blood loss upon vessel injury.
The three phases of hemostasis involve many clotting factors present in plasma and several substances released by platelets and injured tissue cells. It is a fast, localized, and...
The three phases of hemostasis involve many clotting factors present in plasma and several substances released by platelets and injured tissue cells. It is a fast, localized, and...
Clot Retraction and Fibrinolysis
After a fibrin clot is formed, the next step is clot retraction, a vital process facilitated by platelet contractile proteins, such as actin and myosin. These proteins pull the fibrin strands closer together and condense the clot. This action reduces the size of the clot, creating a smaller, denser structure that effectively seals off the damaged vessel. Clot retraction consolidates the clot and helps with wound healing by bringing the edges of the damaged blood vessel closer together.