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A Protocol for Comprehensive Assessment of Bulbar Dysfunction in Amyotrophic Lateral Sclerosis (ALS)

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Published on: February 21, 2011

[Parry-Romberg syndrome with dysphonia].

M A Rafai¹, F Z Boulaajaj, B El Moutawakil

¹Service de neurologie - explorations fonctionnelles, CHU Ibn Rochd, Casablanca, Maroc. mo.mi2@caramail.com

Revue Neurologique

|March 22, 2008

Summary

Parry-Romberg syndrome, a condition causing facial atrophy, can be associated with dysphonia. This case highlights the varied presentations of this rare disorder.

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Area of Science:

Neurology
Dermatology
Genetics

Background:

Parry-Romberg syndrome is a rare condition characterized by progressive hemifacial atrophy.
It often presents with linear scleroderma 'en coup de sabre' and is associated with neurological disorders like seizures.
The etiology of Parry-Romberg syndrome remains poorly understood, with potential links to autoimmune, infectious, or neurological factors.

Observation:

A case of Parry-Romberg syndrome in a 29-year-old male is presented.
The patient exhibited dysphonia, a voice disorder, alongside the characteristic facial atrophy.
Neurological examination and Brain CT scan were normal, ruling out overt central nervous system abnormalities.

Findings:

This report details a rare association between Parry-Romberg syndrome and dysphonia.
The absence of neurological abnormalities on examination and imaging suggests that dysphonia may occur independently of significant central nervous system involvement in this syndrome.
The case expands the known spectrum of Parry-Romberg syndrome manifestations.

Implications:

Understanding the diverse clinical manifestations of Parry-Romberg syndrome is crucial for accurate diagnosis and management.
Further research into the underlying mechanisms of Parry-Romberg syndrome is needed to elucidate its etiology and guide therapeutic strategies.
Management may require a multidisciplinary approach, including reconstructive surgery, symptomatic treatment, and psychological support.