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Updated: Jul 6, 2026
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Pediatric Animal Model of Extracorporeal Cardiopulmonary Resuscitation After Prolonged Circulatory Arrest
Published on: May 26, 2023
Hemostasis management in pediatric mechanical circulatory support
Kerstin Seibel1, Pascal Berdat, Colette Boillat
1Pediatric Intensive Care Unit, Inselspital, Bern, Switzerland.
The Annals of Thoracic Surgery
|March 22, 2008
Summary
Bridging to heart transplantation using the Berlin Heart Excor device was successful in a pediatric patient. Long-term use presented challenges with infection and hypercoagulability, requiring device management.
Area of Science:
- Pediatric cardiology
- Mechanical circulatory support
- Transplantation medicine
Background:
- Mechanical circulatory support (MCS) devices are crucial for pediatric patients awaiting heart transplantation.
- The Berlin Heart Excor is an external biventricular device used for pediatric bridge-to-transplant therapy.
Observation:
- A 9-year-old boy utilized the Berlin Heart Excor for 7 months as a bridge to transplantation.
- The patient experienced significant complications, including device-related infections and hypercoagulability.
Findings:
- Six pump exchanges were necessary due to internal clotting, despite the absence of thromboembolic events.
- Effective hemostasis monitoring and management were critical for the long-term support duration.
Implications:
- This case highlights the complexities of long-term mechanical circulatory support in children.
- Optimized management strategies are essential to mitigate complications like infection and hypercoagulability in pediatric MCS patients.
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