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A Microfluidic-based Hydrodynamic Trap for Single Particles

A Microfluidic-based Hydrodynamic Trap for Single Particles

Published on: January 21, 2011

Development and application of needle trap devices.

In-Yong Eom¹, Anca-Maria Tugulea, Janusz Pawliszyn

¹Department of Chemistry, University of Waterloo, Ontario, Canada.

Journal of Chromatography. A

|March 22, 2008

Summary

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New needle trap devices (NTDs) offer solvent-free sample preparation for analyzing benzene, toluene, ethylbenzene, and xylene (BTEX). Carboxen-packed NTDs demonstrated superior performance for BTEX sampling from air and various indoor sources.

Area of Science:

Analytical Chemistry
Environmental Science

Background:

Solid-phase microextraction (SPME) and needle trap devices (NTDs) offer solvent-free sample preparation.
Developing efficient NTDs is crucial for analyzing volatile organic compounds in air.

Purpose of the Study:

To prepare, characterize, and evaluate novel NTDs packed with divinylbenzene (DVB) or Carboxen 1000 particles.
To optimize sampling parameters and assess the performance of these NTDs for benzene, toluene, ethylbenzene, and xylene (BTEX) analysis.

Main Methods:

Fabrication and characterization of DVB- and Carboxen-packed NTDs.
Optimization of sampling flow rate, breakthrough volume studies, and evaluation of storage stability and reusability.
Application of NTDs for BTEX analysis from diverse air sources, including indoor environments and emissions from common products.

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Main Results:

A maximum sampling flow rate of 1.9 mL/min was determined for NTDs with <1mg sorbent, preventing BTEX breakthrough.
Carboxen-packed NTDs exhibited higher breakthrough volumes compared to DVB-packed NTDs for all BTEX components.
NTDs successfully sampled and analyzed BTEX from permanent marker fumes, mosquito coil smoke, and indoor air, detecting toluene at 10 pg/mL in a garage.

Conclusions:

Home-made NTDs packed with DVB or Carboxen are effective for one-step, solvent-free BTEX sampling and analysis.
Carboxen-packed NTDs offer enhanced capacity for BTEX, suitable for diverse environmental and indoor air monitoring applications.
The developed NTDs provide a sensitive method for detecting low concentrations of BTEX in complex matrices.