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Related Experiment Videos

Contraception with progestogens and progesterone during lactation.

M M Shaaban1

  • 1Department of Obstetrics and Gynecology, Faculty of Medicine, Assiut University, Egypt.

The Journal of Steroid Biochemistry and Molecular Biology
|January 1, 1991
PubMed
Summary

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Breastfeeding mothers can safely use Norplant contraceptive implants and progesterone vaginal rings. These methods do not impact infant growth, development, or breastfeeding performance, offering safe postpartum contraception options.

Area of Science:

  • Reproductive Endocrinology
  • Maternal-Child Health
  • Contraception

Background:

  • Postpartum women require safe and effective contraceptive options.
  • Concerns exist regarding the impact of hormonal contraceptives on breastfeeding and infant development.

Purpose of the Study:

  • To evaluate the safety and efficacy of Norplant (levonorgestrel implants) and a natural progesterone vaginal ring in breastfeeding mothers.
  • To assess the impact of these contraceptives on infant growth, development, and breastfeeding performance.

Main Methods:

  • Comparative study involving 120 women using Norplant, 120 using injectable norethisterone enanthate, and 120 using IUDs.
  • Infant growth, health, and psychomotor development milestones were monitored.
  • A separate study evaluated a progesterone vaginal ring in breastfeeding mothers, monitoring serum progesterone levels and infant outcomes.
Keywords:
AfricaArab CountriesBiodegradable Delivery SystemsBiologyBody WeightBreast FeedingChild DevelopmentClinical ResearchContraceptionContraception ContinuationContraception FailureContraceptive AgentsContraceptive Agents, FemaleContraceptive Agents, ProgestinContraceptive EffectivenessContraceptive ImplantsContraceptive MethodsContraceptive UsageDeveloping CountriesEgyptEndocrine SystemEstradiolEstrogensFamily PlanningGrowthHealthHormonesHuman VolunteersInfant NutritionInjectablesIudIud, Copper ReleasingLevonorgestrelMediterranean CountriesMethod AcceptabilityNorthern AfricaNutritionNutrition IndexesOrganization And AdministrationOvulationPhysiologyPostpartum WomenProgestational HormonesProgesteroneProgram AccessibilityProgram EvaluationProgramsPuerperiumReproductionResearch MethodologyResearch ReportSupplementary FeedingUltrasonicsUse-effectivenessVaginal RingsWeaning

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Main Results:

  • No significant differences in breastfeeding performance, infant physical growth, health, or psychomotor development were observed between groups using Norplant, injectable contraceptives, or IUDs.
  • The progesterone vaginal ring effectively augmented lactational infertility, was well-tolerated, and showed no adverse effects on breastfeeding or infant outcomes.
  • Natural progesterone's low absorption in the infant gut suggests an added safety profile.

Conclusions:

  • Norplant and the natural progesterone vaginal ring are potential safe and effective contraceptive options for breastfeeding mothers.
  • These methods can be initiated early postpartum, providing flexible family planning choices.