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Related Concept Videos

Positron Emission Tomography01:29

Positron Emission Tomography

Positron emission tomography (PET) is a medical imaging technique involving radiopharmaceuticals — substances that emit short-lived radiation. Although the first PET scanner was introduced in 1961, it took 15 more years before radiopharmaceuticals were combined with the technique and revolutionized its potential.
One of the main requirements of a PET scan is a positron-emitting radioisotope, which is produced in a cyclotron and then attached to a substance used by the part of the body being...

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Diffuse FDG uptake in acute prostatitis.

Pan-Fu Kao1, Yu-Hsiang Chou, Chieh-Wen Lai

  • 1Department of Nuclear Medicine, Buddhist Tzu Chi General Hospital, Taipei Branch, 289 Jianguo Road, Xindian City, Taipei 231, Taiwan. kaopanfu@tzuchi.com.tw

Clinical Nuclear Medicine
|March 22, 2008
PubMed
Summary
This summary is machine-generated.

A 77-year-old man with back pain was diagnosed with chronic osteomyelitis of the lumbar spine. Further tests revealed an enlarged prostate with inflammation, not cancer, despite elevated prostate-specific antigen levels.

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Area of Science:

  • Oncology
  • Infectious Diseases
  • Radiology

Background:

  • A 77-year-old male presented with intractable back pain, prompting imaging studies.
  • Initial investigations included whole body bone scan and abdominal computed tomography (CT).

Observation:

  • Imaging revealed a destructive bone lesion in the lumbar spine.
  • F-18 FDG PET/CT showed intense uptake in an enlarged prostate and mild uptake in the lumbar spine.
  • The patient exhibited pyuria, mild fever, and elevated serum prostate-specific antigen (PSA).

Findings:

  • Blood culture identified Klebsiella pneumoniae.
  • Prostate biopsy indicated acute inflammation, ruling out malignancy.
  • Lumbar spine biopsy confirmed chronic osteomyelitis.

Implications:

  • This case highlights the importance of considering infectious etiologies, such as osteomyelitis, in patients with suspected malignancy and elevated PSA.
  • F-18 FDG PET/CT can aid in differentiating inflammatory conditions from cancer.
  • Prompt identification and treatment of infectious agents like Klebsiella pneumoniae are crucial.