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Updated: Jul 6, 2026
Conjunctival Commensal Isolation and Identification in Mice
Published on: May 1, 2021
In vitro antibiotic susceptibility of preoperative normal conjunctival bacteria
C N Ta1, L He, H Mino de Kaspar
1Department of Ophthalmology, School of Medicine, Stanford University, Stanford, CA 94305, USA. cta@ stanford.edu
Purpose:
To determine the antibiotic susceptibility of preoperative conjunctival bacterial flora.
Methods:
Antibiotic susceptibility of conjunctival bacterial strains isolated from 142 patients undergoing intraocular surgery was determined using the Kirby-Bauer disc diffusion technique. chi(2) statistical analysis was performed.
Results:
Among the 116 bacteria isolated, 95 (82%) were coagulase-negative staphylococci (CNS). Most (>75%) of them were susceptible to vancomycin, minocycline, aminoglycosides, gatifloxacin, levofloxacin, and moxifloxacin. Approximately one-half of CNS was resistant to erythromycin and azithromycin. Over 90% of streptococci were susceptible to levofloxacin, moxifloxacin, and gatifloxacin.
Results:
Fluoroquinolones, specifically gatifloxacin, levofloxacin, and moxifloxacin continue to provide broad-spectrum coverage against common conjunctival bacterial flora.
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