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Use of Viral Entry Assays and Molecular Docking Analysis for the Identification of Antiviral Candidates against Coxsackievirus A16
Published on: July 15, 2019
Pediatric group B coxsackievirus infections
1University of Nebraska Medical Center, 986495 Nebraska Medical, Omaha, NE 68198-6495, USA. jrromero@unmc.edu
Current Topics in Microbiology and Immunology
|March 25, 2008
Summary
Coxsackievirus (CVB) infections are common in children, spreading mainly through the fecal-oral route but also from mother to infant. This review covers clinically relevant CVB syndromes, diagnosis, treatment, and prevention strategies.
Area of Science:
- Pediatric Infectious Diseases
- Virology
- Public Health
Background:
- Enteroviruses, specifically Coxsackievirus (CVB), are significant pathogens in infants and children.
- CVB infections pose a considerable health burden on pediatric populations worldwide.
- Understanding transmission routes is crucial for effective control.
Purpose of the Study:
- To review common and clinically relevant Coxsackievirus (CVB) related syndromes in children.
- To provide an overview of diagnostic methods for CVB infections.
- To discuss current treatment and prevention strategies for CVB.
Main Methods:
- Literature review of existing studies on Coxsackievirus (CVB).
- Focus on clinically relevant syndromes, diagnosis, treatment, and prevention.
- Synthesis of information on transmission routes, including fecal-oral and vertical transmission.
Main Results:
- CVB are established pediatric pathogens with diverse clinical manifestations.
- Fecal-oral transmission is the primary route, but vertical transmission also occurs.
- Effective diagnosis, treatment, and prevention are essential for managing CVB infections.
Conclusions:
- Coxsackievirus (CVB) infections require comprehensive management strategies in pediatric care.
- Continued research into diagnosis, treatment, and prevention is vital.
- Public health efforts should focus on interrupting transmission routes.
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