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Related Experiment Video

Updated: Jul 6, 2026

Postoperative Ileus Murine Model
04:26

Postoperative Ileus Murine Model

Published on: July 12, 2024

Postoperative ileus after total joint arthroplasty.

Javad Parvizi1, Seung-Beom Han, T David Tarity

  • 1Rothman Institute of Orthopedics at Thomas Jefferson Hospital, Seoul, South Korea.

The Journal of Arthroplasty
|March 25, 2008
PubMed
Summary

Postoperative ileus (POI) affects 0.7% of patients after joint replacement. Risk factors include older age, male sex, hip surgery, and prior abdominal surgery, but not narcotic use in this study.

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Published on: September 7, 2022

Area of Science:

  • Orthopedic Surgery
  • Gastroenterology
  • Anesthesiology

Background:

  • Postoperative ileus (POI) is a common complication following major surgery.
  • Optimizing pain management and anesthesia may reduce POI incidence.

Purpose of the Study:

  • To determine the incidence and identify risk factors for POI in patients undergoing total joint arthroplasty.
  • To evaluate the impact of regional anesthesia and multimodal pain management on POI.

Main Methods:

  • Retrospective analysis of 4567 patients undergoing total joint arthroplasty between January 2004 and December 2005.
  • Utilized regional anesthesia and multimodal pain management protocols.
  • Identified patient demographics, surgical factors, and outcomes related to POI.

Main Results:

  • The incidence of POI was 0.7% (31/4567 patients).
  • Identified risk factors for POI included older age, male sex, hip arthroplasty, and prior abdominal surgery.
  • Narcotic medication type and dosage did not significantly influence POI development under the study's protocol.

Conclusions:

  • POI is infrequent but carries significant risks, including mortality and perforation.
  • Older age, male sex, hip arthroplasty, and prior abdominal surgery are key risk factors for POI.
  • Current multimodal pain management protocols may mitigate the impact of narcotics on POI.