Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

The likelihood ratio test for the two-component normal mixture problem: power and sample size analysis.

N R Mendell1, H C Thode, S J Finch

  • 1Department of Applied Mathematics and Statistics, University at Stony Brook, New York 11794.

Biometrics
|September 11, 1991
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Initial chest radiograph scores inform COVID-19 status, intensive care unit admission and need for mechanical ventilation.

Clinical radiology·2021
Same author

Missed myocardial infarctions in ED patients prospectively categorized as low risk by established risk scores.

The American journal of emergency medicine·2017
Same author

Rocks, soils, and water quality. Relationships and implications for effects of acid precipitation on surface water in the Northeastern United States.

Environmental science & technology·2012
Same author

The power and robustness of maximum LOD score statistics.

Annals of human genetics·2008
Same author

Tradeoff between no-call reduction in genotyping error rate and loss of sample size for genetic case/control association studies.

Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing·2004
Same author

Errors and linkage disequilibrium interact multiplicatively when computing sample sizes for genetic case-control association studies.

Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing·2003
Same journal

Fast penalized generalized estimating equations for large longitudinal functional datasets.

Biometrics·2026
Same journal

Causally-interpretable random-effects meta-analysis.

Biometrics·2026
Same journal

Statistical inference for mean function of partially observed functional time series.

Biometrics·2026
Same journal

Subgroup identification via Interaction Tree and Mixed Model for Repeated Measures with application to Alzheimer's disease.

Biometrics·2026
Same journal

Finite mixtures of linear quantile regressions with concomitant variables: a solution to endogeneity in longitudinal data modeling.

Biometrics·2026
Same journal

Discussion on "INTACT: a method for integration of longitudinal physical activity data from multiple sources" by Jingru Zhang, Erjia Cui, Hongzhe Li, and Haochang Shou.

Biometrics·2026
See all related articles

This study models the likelihood ratio test for two-component mixtures, finding power depends on mixing proportion. Sample sizes are estimated for various statistical power levels and mixture compositions.

Area of Science:

  • Statistics
  • Statistical modeling

Background:

  • Likelihood ratio tests are crucial for statistical inference.
  • Understanding mixture distributions is vital in various scientific fields.

Purpose of the Study:

  • To approximate the alternative distribution of the likelihood ratio test for two-component mixtures.
  • To determine the impact of mixing proportions on statistical power and required sample sizes.

Main Methods:

  • Simulation and mathematical modeling were employed.
  • The study analyzed mixtures with differing means but equal variances.
  • A range of mixing proportions (0.5 to 0.95) were considered.

Main Results:

  • Statistical power demonstrated dependence on mixing proportion, particularly for extreme values ( < 0.2 and > 0.80).

Related Experiment Videos

  • The alternative distribution was approximated as noncentral chi-square, potentially with 2 degrees of freedom.
  • Sample size estimations were provided for 50%, 80%, and 90% power across different mixing proportions.
  • Conclusions:

    • The noncentral chi-square approximation aids in sample size determination for mixture analysis.
    • Specific sample sizes are required to achieve desired power, varying with mixture composition.