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Updated: Jul 6, 2026

Multimodal Cross-Device and Marker-Free Co-Registration of Preclinical Imaging Modalities
Published on: October 27, 2023
Immobilization device for in vivo and in vitro multimodality image registration of rodent tumors
Nicolas Christian1, John A Lee, Anne Bol
1Center for Molecular Imaging and Experimental Radiotherapy, Université Catholique de Louvain, Brussels, Belgium.
Abstract:
Biological image-guided radiotherapy requires that PET accurately identifies biologically relevant sub-volumes within a tumor. In this framework, an immobilization device was developed to study multi-imaging (CT, micro-MRI, micro-PET, and autoradiography) registration of mouse tumors. The registration accuracy assessed by calculating the average minimal distance between two skew lines was in the order of 0.2-0.3 mm.
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