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06:45
Histological-Based Stainings Using Free-Floating Tissue Sections
Published on: August 25, 2020
Hematidrosis: a pathologic process or stigmata. A case report with comprehensive histopathologic and immunoperoxidase
Jane Manonukul1, Wanee Wisuthsarewong, Rattanavalai Chantorn
1Department of Pathology, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand. sijmn@mahidol.ac.th
The American Journal of Dermatopathology
|March 25, 2008
Summary
Hematidrosis, or bloody sweat, is a rare condition. This study explains the cause of bleeding through skin pores and follicular canals, clarifying its intermittent nature.
Area of Science:
- Dermatology
- Pathology
Background:
- Hematidrosis, or bloody sweat, is an extremely rare condition.
- Historically, it has been associated with religious beliefs and stigmatization.
Observation:
- A case of hematidrosis in a 14-year-old girl is presented, with bleeding from the scalp, palms, trunk, soles, and legs.
- Bloody sweat from the scalp contained all blood elements.
Findings:
- Biopsy revealed blood-filled spaces opening into follicular canals or onto the skin surface.
- Immunoperoxidase studies ruled out a vascular origin for these spaces.
- The study elucidates the mechanism of bleeding and its intermittent recurrence due to the cyclical nature of these spaces.
Implications:
- Provides a scientific explanation for hematidrosis, differentiating it from supernatural or stigmatized phenomena.
- Clarifies the pathophysiology of this rare condition, aiding in diagnosis and understanding.
- Contributes to the medical literature by explaining the intermittent nature of bloody sweat.
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