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The controversy surrounding OxyContin abuse: issues and solutions.

Sujata S Jayawant, Rajesh Balkrishnan

Therapeutics and Clinical Risk Management

|March 25, 2008

Summary

OxyContin (oxycodone hydrochloride) abuse became an epidemic, fueled by its euphoric effects and media attention. Solutions include pharmacist risk assessments and tamper-resistant prescriptions to curb misuse.

Area of Science:

Pharmacology
Public Health
Addiction Medicine

Background:

OxyContin (oxycodone hydrochloride) abuse has reached epidemic proportions.
The prescription analgesic's street popularity stems from its heroin-like euphoric effects.
Media attention and "black box" warnings may have contributed to abuse and diversion.

Purpose of the Study:

To overview controversies surrounding OxyContin abuse.
To discuss solutions for managing prescription analgesic misuse.
To identify strategies for preventing OxyContin diversion and abuse.

Main Methods:

Literature search of MEDLINE (1990-2004).
Comprehensive internet search for recent updates and government reports.
Analysis of regulatory actions and manufacturer initiatives.

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Main Results:

OxyContin's euphoric effects led to its use as a street drug.
Regulatory bodies and manufacturers initiated actions to address abuse.
Several strategies were proposed to manage OxyContin misuse.

Conclusions:

Community pharmacist risk assessments can identify potential medication abuse.
Physician education on risk management is crucial.
Tamper-resistant prescription pads offer a plausible, immediate solution to control abuse.