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Updated: Jul 6, 2026

Occlusion of the Great and Small Saphenous Vein Using Copolymeric Glue Based on N-Butyl Cyanoacrylate and Methacryloxy Sulfolane
Published on: December 9, 2022
Classification of saphenous refluxes: implications for treatment
P Pittaluga1, S Chastane, B Rea
1Riviera Veine Institut, Nice, France. paulpittaluga@hotmail.com
Objective:
To determine the possible correlations of patient age, symptoms and signs with findings of Doppler duplex examination in limbs with varicose veins.
Methods:
A total of 2275 ultrasound examinations were done on 2275 limbs of 1751 patients (421 men and 1330 women). Ages ranged from 21 to 94 years (mean 50). Symptoms of aching, heaviness, burning pain (venous neuropathy) were recorded, and signs of ankle hyperpigmentation, scars of healed ulcers and presence of open venous ulcers were noted.
Results:
Presence of symptoms was associated with advancing patient age (50.7 vs. 48.8 years). Varicose veins without great saphenous reflux correlated with younger age (43 vs. 53.5 years). Presence of saphenofemoral junctional incompetence correlated with an older age (54.7 vs. 49.8 years), and reflux to the ankle (Hach stage IV) also correlated with older age (mean 63.7 years). A younger age was associated with less advanced signs (C0-C2: 49.1 vs. C4-C6: 60.1 years). Saphenous vein reflux without clinical varices was associated with more advanced signs (C4-C6: 21.3%).
Conclusions:
Ageing is associated with advancing clinical symptoms, signs and increasing multifocal reflux in limbs with venous insufficiency. These facts support the concept of early treatment of venous insufficiency before predictable deterioration occurs.
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