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Spinal manipulation and mobilisation for back and neck pain: a blinded review
B W Koes1, W J Assendelft, G J van der Heijden
1Department of Epidemiology and Biostatistics, University of Limburg, Maastricht, The Netherlands.
Objective:
To assess the efficacy of spinal manipulation for patients with back or neck pain.
Design:
Computer aided search for published papers and blinded assessment of the methods of the studies.
Subjects:
35 randomised clinical trials comparing spinal manipulation with other treatments.
Main Outcome Measures:
Score for quality of methods (based on four main categories: study population, interventions, measurement of effect, and data presentation and analysis) and main conclusion of author(s) with regard to spinal manipulation.
Results:
No trial scored 60 or more points (maximum score 100) suggesting that most were of poor quality. Eighteen studies (51%) showed favourable results for manipulation. In addition, five studies (14%) reported positive results in one or more subgroups. Of the four studies with 50-60 points, one reported that manipulation was better, two reported that manipulation was better in only a subgroup, and one reported that manipulation was no better or worse than reference treatment. Eight trials attempted to compare manipulation with some placebo, with inconsistent results.
Conclusions:
Although some results are promising, the efficacy of manipulation has not been convincingly shown. Further trials are needed, but much more attention should be paid to the methods of study.