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Updated: Jul 6, 2026

Investigation of Xenobiotics Metabolism In Salix alba Leaves via Mass Spectrometry Imaging
Published on: June 15, 2020
Phytochemical investigation on leaf extract of Cordia salicifolia Cham
Luigi Menghini1, Francesco Epifano, Lidia Leporini
1Dipartimento di Scienze del Farmaco, University G. D'Annunzio, Chieti Scalo, Italy. lmenghini@unich.it
Abstract:
The dichloromethane extract of leaves of Cordia salicifolia Cham. (Family Boraginaceae) was fractionated by SiO(2) column chromatography and analyzed by gas chromatography, gas chromatography-mass spectrometry, and nuclear magnetic resonance spectroscopy. The apolar extract is characterized by a very high content of (+)-spathulenol (0.53%). The major component of the extract exhibited a very weak activity as an inhibitor of growth of Helicobacter pylori in vitro (minimum inhibitory concentration = 200 microg/mL).
