Related Experiment Video
Updated: Jul 6, 2026

Dried Blood Spots - Preparing and Processing for Use in Immunoassays and in Molecular Techniques
Published on: March 13, 2015
Screening for hepatitis C in sexual health clinic attendees
M Cristina Mapagu1, Sarah J Martin, Marian J Currie
1Westmead Hospital, PO Box 533, Wentworthville, NSW 2145, Australia.
Insights
Routine Hepatitis C virus (HCV) screening in sexual health clinics is effective. Clinician-led risk assessment accurately identified most HCV infections, demonstrating its value in detecting the virus.
Area of Science:
- Hepatology
- Infectious Diseases
- Public Health
Background:
- Hepatitis C virus (HCV) prevalence is elevated in sexual health clinic attendees.
- Screening strategies include risk assessment or universal testing.
- This audit evaluated routine HCV screening in a sexual health center.
Purpose of the Study:
- To assess the effectiveness of routine Hepatitis C virus screening.
- To determine the value of clinician-led risk assessment for HCV detection.
Main Methods:
- Retrospective audit of medical records and pathology data (2000-2002).
- Analysis of 3845 HCV tests from 3156 individuals.
- Identification of known diagnoses and risk factors at the time of testing.
Main Results:
- 95 patients (3.0%) had confirmed HCV infection; 29 (30.5%) were new diagnoses.
- Injecting drug use was reported by 85.3% of patients with HCV.
- Risk factor assessment identified all but one positive case.
Conclusions:
- Clinician-led risk assessment is an effective strategy for HCV screening.
- Routine HCV testing in sexual health centers can identify new cases.
Introduction:
Hepatitis C virus (HCV) prevalence has been shown to be higher in some sexual health clinic attendees than the general population. Screening for HCV in sexual health clinics may be based on risk assessment or universal screening. The aim of this audit was to explore the value of routine HCV screening in a sexual health centre population.
Methods:
Medical records and pathology data concerning all patients tested for HCV between 2000 and 2002 at Canberra Sexual Health Centre were audited to determine whether the diagnosis of HCV was already known and which, if any, risk factors were identified at the time of testing.
Results:
A total of 3845 tests were conducted on 3156 individuals over the 3-year period. HCV seropositivity was confirmed in 95 patients (3.0%; 95% CI 2.4-3.7), of which 29 (30.5%) were new diagnoses. A total of 85.3% of all patients with confirmed HCV infection reported a history of injecting drug use. Tattoos and body piercings were the most common risk factor in those who denied ever injecting. Risk factor assessment correctly identified all but one positive patient.
Conclusions:
HCV testing based on clinician-led risk assessment is an effective approach to HCV screening.
Related Concept Videos
Hepatitis
Genital Herpes
Sexually Transmitted Infections
Viral Hepatitis I: Introduction