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Coronary Progenitor Cells and Soluble Biomarkers in Cardiovascular Prognosis after Coronary Angioplasty
10:03

Coronary Progenitor Cells and Soluble Biomarkers in Cardiovascular Prognosis after Coronary Angioplasty

Published on: January 28, 2020

[The high-sensitivity C-reactive protein level one month after bare-metal coronary stenting may predict late adverse

Juan-Antonio Fournier1, Carmen Delgado-Pecellín, Aurelio Cayuela

  • 1Servicio de Cardiología, Hospital Universitario Virgen del Rocío, Sevilla, España. jafournier@gmail.com

Revista Espanola De Cardiologia
|March 26, 2008
PubMed

Insights

High-sensitivity C-reactive protein (hs-CRP) levels 30 days post-PCI predict cardiac events. Lower hs-CRP levels correlate with better event-free survival after stenting.

Area of Science:

  • Cardiology
  • Biomarkers
  • Interventional Cardiology

Context:

  • Percutaneous coronary interventions (PCIs) are common procedures.
  • The prognostic value of high-sensitivity C-reactive protein (hs-CRP) after PCI remains uncertain.
  • Bare-metal stents are frequently used in PCI procedures.

Purpose:

  • To investigate the predictive significance of hs-CRP levels in patients undergoing PCI.
  • To determine if hs-CRP levels can identify patients at risk for adverse cardiac events post-stenting.

Summary:

  • hs-CRP and Troponin-T levels were monitored in 68 patients before and after PCI with bare-metal stents.
  • Elevated hs-CRP levels at 24 hours and 30 days post-PCI were associated with adverse events.
  • hs-CRP levels at 30 days demonstrated high sensitivity (80%) and specificity (72%) for predicting events.
  • Event-free survival at 12 months was significantly better for patients with hs-CRP ≤2.5 mg/L at 30 days.

Impact:

  • Measuring hs-CRP 30 days after stenting may aid in predicting late adverse cardiac events.
  • This finding could refine risk stratification and patient management following PCI.
  • hs-CRP serves as a valuable prognostic biomarker in the context of coronary stenting.

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