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Related Concept Videos

Increased Intracranial Pressure l: Introduction01:14

Increased Intracranial Pressure l: Introduction

Intracranial hypertension is a sustained elevation of intracranial pressure (ICP) above 22 mm Hg. In supine adults, normal ICP is ~7–15 mm Hg.The rigid, nonexpandable cranium contains three components—brain tissue, blood, and cerebrospinal fluid (CSF)—that total ~1,700 mL in a typical adult: 1,400 mL brain (~80%), 150 mL blood (~10%), and 150 mL CSF (~10%). According to the Monro–Kellie doctrine, total intracranial volume is effectively fixed. When one component expands, CSF and venous blood...
Increased Intracranial Pressure ll: Pathophysiology01:29

Increased Intracranial Pressure ll: Pathophysiology

Increased intracranial pressure (ICP) refers to a potentially life-threatening rise in pressure inside the skull. This usually happens when there is a major change in the volume of brain tissue, blood, or cerebrospinal fluid (CSF) — the three components inside the skull. According to the Monro-Kellie doctrine, if the volume of one component increases, the volumes of the other components must decrease to maintain normal pressure. If this does not happen, ICP rises.The process often begins with...
Cerebral Edema ll: Pathophysiology01:22

Cerebral Edema ll: Pathophysiology

Vasogenic edema is a major form of cerebral edema characterized by abnormal accumulation of fluid in the brain’s extracellular space due to disruption of the blood–brain barrier (BBB). The BBB is a specialized structure composed of endothelial cells connected by tight junctions, supported by astrocytic endfeet and a basement membrane. Under normal conditions, it tightly regulates the movement of ions, proteins, and solutes between the bloodstream and brain parenchyma. When this barrier loses...
Cerebral Edema l: Introduction01:19

Cerebral Edema l: Introduction

Cerebral edema is a pathological increase in brain water content that disrupts intracranial pressure regulation and impairs neurological function. Because the cranial vault is rigid, even modest increases in tissue volume can compromise cerebral perfusion, distort neural structures, and initiate secondary injury. Cerebral edema develops through four principal mechanisms: vasogenic, cytotoxic, interstitial, and ionic.Vasogenic EdemaVasogenic edema arises from disruption of the blood–brain...
Cerebrospinal Fluid01:21

Cerebrospinal Fluid

Cerebrospinal fluid (CSF) is a colorless liquid that flows around the brain and the spinal cord, playing a vital role in the protection, support, and overall function of the central nervous system (CNS). CSF production, circulation, and absorption are tightly regulated processes essential for the brain and spinal cord to function properly.
CSF Production
CSF is produced mainly in the choroid plexus, a network of capillaries and ependymal cells located within the ventricular system of the brain.
Bacterial Meningitis II: Pathophysiology01:26

Bacterial Meningitis II: Pathophysiology

Bacterial meningitis typically begins when pathogens such as Neisseria meningitidis and Streptococcus pneumoniae colonize the nasopharynx and invade the bloodstream. This process is facilitated by bacterial virulence factors, such as polysaccharide capsules, which resist phagocytosis and complement-mediated killing. Less commonly, bacteria reach the central nervous system via contiguous spread from infections like otitis media or sinusitis, through congenital or acquired dural defects, or...

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Updated: Jul 6, 2026

A Detailed Protocol for Physiological Parameters Acquisition and Analysis in Neurosurgical Critical Patients
05:01

A Detailed Protocol for Physiological Parameters Acquisition and Analysis in Neurosurgical Critical Patients

Published on: October 17, 2017

Does brain temperature correlate with intracranial pressure?

Gerald Huschak1, Thomas Hoell, Martin Wiegel

  • 1Departments of Neurosurgery, BG Kliniken Bergmannstrost, Halle, Germany. Gerald.huschak@gmx.de

Journal of Neurosurgical Anesthesiology
|March 26, 2008
PubMed
Summary

This study found no significant clinical correlation between brain temperature and intracranial pressure (ICP) in intensive care patients. The weak relationship suggests brain temperature monitoring may not be useful for managing ICP.

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A Detailed Protocol for Physiological Parameters Acquisition and Analysis in Neurosurgical Critical Patients
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A Bedside, Single Burr Hole Approach to Multimodality Monitoring in Severe Brain Injury
06:18

A Bedside, Single Burr Hole Approach to Multimodality Monitoring in Severe Brain Injury

Published on: March 26, 2019

Area of Science:

  • Neuroscience
  • Critical Care Medicine
  • Biomedical Engineering

Background:

  • A proposed positive correlation exists between brain temperature and intracranial pressure (ICP) in intensive care settings.
  • Understanding this relationship is crucial for managing neurocritical care patients.

Purpose of the Study:

  • To investigate the correlation between brain temperature and intracranial pressure (ICP) in intensive care patients.
  • To determine if this correlation is clinically significant.

Main Methods:

  • Collected simultaneous brain temperature and ICP data at 5-minute intervals from 40 neurosurgical patients.
  • Utilized ICP/temperature probes and urinary catheter probes for measurements.
  • Analyzed data using Pearson correlation and time series analysis.

Main Results:

  • Brain temperature was slightly higher than core temperature (median difference 0.3°C, P<0.001).
  • The mean Pearson correlation coefficient (re) between ICP and brain temperature was 0.13 (P<0.05).
  • Time series analysis showed a mean correlation of 0.05±0.25 (P<0.05), with less than 2% of variability explained.

Conclusions:

  • The study found no clinically useful correlation between brain temperature and ICP.
  • These findings do not support the use of brain temperature as a direct indicator for ICP management.