Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Rheumatic Heart Disease III: Medical Management

Rheumatic Heart Disease III: Medical Management

Rheumatic heart disease (RHD) management can be divided into two main strategies: prevention and long-term management.Primary PreventionPrimary prevention focuses on timely diagnosis and management of group A streptococcal pharyngitis to prevent acute rheumatic fever. The most widely used antibiotic for treating this condition is intramuscular benzathine penicillin G.Acute Rheumatic Fever TreatmentThe primary treatment goal for a patient diagnosed with acute rheumatic fever is to suppress the...

Rheumatic Heart Disease IV: Nursing Management

Rheumatic Heart Disease IV: Nursing Management

AssessmentA comprehensive assessment is essential in managing a patient with rheumatic heart disease (RHD). Begin with obtaining a detailed medical history, including recent streptococcal infections, a history of rheumatic fever, or previously diagnosed rheumatic heart disease. Assess the patient for symptoms such as fever, chest pain, widespread joint pain (arthralgia), tachycardia, pericardial friction rub, muffled heart sounds, heart murmurs, peripheral edema, subcutaneous nodules, and...

Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies

Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies

The key clinical manifestations of Rheumatic heart disease (RHD) include several distinct cardiac symptoms.Carditis, a hallmark of acute rheumatic fever, involves inflammation of the heart's endocardium, myocardium, and pericardium. Chronic RHD often results from recurrent episodes of carditis. Its symptoms include the following:Murmurs are caused by valvular damage, especially to the mitral and aortic valves. Mitral stenosis or regurgitation is common, with characteristic heart murmurs...

Skeletal Muscle Relaxants: Therapeutic Uses

Skeletal Muscle Relaxants: Therapeutic Uses

Skeletal muscle relaxants are used to relax muscle tone and alleviate painful muscle contractions. However, the choice of skeletal muscle relaxants depends on the duration of the surgical procedure in order to minimize potential side effects. Skeletal muscle relaxants like neuromuscular blocking agents [NMBAs] are commonly employed as adjuvants alongside general anesthetics in clinical settings. NMBAs are also used to maintain controlled ventilation during surgery of the larynx or pharynx as...

Chronic Pancreatitis II: Collaborative Care

Chronic Pancreatitis II: Collaborative Care

The management of chronic pancreatitis is multifaceted, involving a comprehensive approach that includes thorough assessment, diagnostic testing, and a variety of management strategies.
Assessment:

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

The Role of Dexketoprofen/Tramadol in Multimodal Therapy to Prevent Acute Postsurgical and Acute Low Back Pain from Developing into Chronic Pain: A Delphi Consensus Study.

Pain and therapy·2025

Same author

Clinical Benefits of Ibuprofen Arginine: A Narrative Review.

Pain and therapy·2025

Same author

Features and management of osteoarthritis from the perspective of individuals with osteoarthritis: A systematic review of qualitative studies.

Osteoarthritis and cartilage open·2025

Same author

Narrative review of the efficacy and safety of the high-concentration (179mg) capsaicin patch in peripheral neuropathic pain with recommendations for clinical practice and future research.

Pain reports·2025

Same author

Fibromyalgia: do I tackle you with pharmacological treatments?

Pain reports·2025

Same author

Neuropathic Component Characteristics in Chronic Secondary Musculoskeletal Pain After Postmenopausal Osteoporotic Fractures: A Pilot Cross-Sectional Study.

Pain research & management·2025

Search research articles

Related Experiment Video

Updated: Jul 6, 2026

A Randomized, Sham-Controlled Trial of Cranial Electrical Stimulation for Fibromyalgia Pain and Physical Function, Using Brain Imaging Biomarkers

A Randomized, Sham-Controlled Trial of Cranial Electrical Stimulation for Fibromyalgia Pain and Physical Function, Using Brain Imaging Biomarkers

Published on: January 5, 2024

Fibromyalgia: harmonizing science with clinical practice considerations.

Serge Perrot¹, Anthony H Dickenson, Robert M Bennett

¹Center de la Douleur et Service de Médecine Interne, Hôtel-Dieu, University Paris 5 Descartes, Paris, France. serge.perrot@htd.aphp.fr

Pain Practice : the Official Journal of World Institute of Pain

|March 28, 2008

Summary

This summary is machine-generated.

Fibromyalgia, a common chronic pain disorder, is increasingly understood to involve central sensitization. Emerging treatments show promise for managing pain, fatigue, and sleep issues associated with this condition.

Related Experiment Videos

Last Updated: Jul 6, 2026

A Randomized, Sham-Controlled Trial of Cranial Electrical Stimulation for Fibromyalgia Pain and Physical Function, Using Brain Imaging Biomarkers

A Randomized, Sham-Controlled Trial of Cranial Electrical Stimulation for Fibromyalgia Pain and Physical Function, Using Brain Imaging Biomarkers

Published on: January 5, 2024

Area of Science:

Rheumatology and Pain Management

Background:

Fibromyalgia is a prevalent chronic pain syndrome in general medicine and rheumatology.
Understanding of fibromyalgia has advanced, paralleling progress in its pathophysiology and clinical description.

Purpose of the Study:

To review current and emerging knowledge on fibromyalgia's pathophysiology, diagnosis, and management.
To provide an overview of the evolving understanding and treatment strategies for fibromyalgia.

Main Methods:

Review of existing literature on fibromyalgia.
Synthesis of information on pathophysiology, diagnosis, and treatment.

Main Results:

Fibromyalgia pain is primarily driven by central sensitization, not peripheral processes.
Pharmacological agents like SNRIs, tramadol, and pregabalin demonstrate efficacy in reducing pain and core symptoms.
Updated management guidelines have been developed by the European League Against Rheumatism.

Conclusions:

Fibromyalgia is a complex condition rooted in central nervous system changes.
Effective management strategies involve pharmacological interventions targeting core symptoms.
Ongoing research and updated guidelines inform clinical practice for fibromyalgia.