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Published on: October 20, 2017
Infectious intracranial aneurysms in the pediatric population: endovascular treatment with Onyx
Christopher S Eddleman1, Daniel Surdell, Arthur DiPatri
1Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA. eddleman@md.northwestern.edu
Insights
Liquid embolics like Onyx offer a safe and effective endovascular treatment for pediatric infectious intracranial aneurysms. Combining Onyx with coils can tailor therapy for successful aneurysm exclusion.
Area of Science:
- Neurology
- Interventional Radiology
- Pediatric Neurosurgery
Background:
- Infectious intracranial aneurysms (IIAs) pose significant treatment challenges in pediatric patients.
- Traditional treatment options for pediatric IIAs have limitations.
- Advancements in endovascular techniques provide new therapeutic avenues.
Observation:
- This study reviews the use of Onyx, a liquid embolic agent, for treating pediatric IIAs.
- The endovascular approach involved embolizing ruptured IIAs with Onyx, either alone or with platinum coils.
- The safety and efficacy of this endovascular strategy were evaluated.
Findings:
- Endovascular therapy using liquid embolics, specifically Onyx, is a safe and effective treatment for pediatric IIAs.
- The combination of Onyx with platinum coils allows for tailored treatment strategies to achieve aneurysm exclusion.
- The study demonstrated good results in excluding infectious aneurysms using these endovascular modalities.
Implications:
- Liquid embolic agents represent a viable and effective treatment option for pediatric infectious intracranial aneurysms.
- Tailored endovascular approaches can achieve successful exclusion of these complex aneurysms.
- Further research is warranted to determine the long-term outcomes of this endovascular treatment in pediatric populations.
Objects:
Infectious intracranial aneurysms present a treatment challenge in the pediatric population. Current endovascular strategies and tools have been developed, which make treatment of infectious intracranial aneurysms with liquid embolics safe and effective. This study reviews the use of the liquid embolic Onyx in the treatment of infectious intracranial aneurysms in the pediatric population.
Materials And Methods:
We used an endovascular approach to treat ruptured infectious intracranial aneurysms. We embolized the aneurysms with either Onyx alone or in combination with platinum coils.
Conclusion:
Endovascular therapy with liquid embolics (Onyx) has been shown to be a safe and effectual treatment option in the case of pediatric infectious intracranial aneurysms. The combination of endovascular modalities can also be used to tailor the therapeutic goal of exclusion of infectious aneurysms with good results. Further studies are needed to assess the long-term effectiveness of this approach to pediatric infectious intracranial aneurysms.
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