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Efficient DNA pairing in a Neurospora mutant defective in chromosome pairing
1Institute of Molecular Biology, University of Oregon, Eugene 97403.
Molecular & General Genetics : MGG
|December 1, 1991
Abstract:
A Neurospora crassa mutation, mei-2, affecting recombination and pairing of homologous chromosomes during meiosis, was characterized for its effect on repeat-induced point mutation (RIP). We found that RIP, which depends on recognition of DNA sequence homology, is not inhibited by mei-2, suggesting that the defect in chromosome pairing of this mutant is not due to a defect in DNA pairing and that DNA pairing is not dependent on chromosome pairing.