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Assessment of quality of life in asthmatic Turkish children

Perran Boran1, Gülnür Tokuç, Burcu Pişgin

  • 12nd Clinic of Pediatrics, Dr. Lutfi Kirdar Kartal Research and Training Hospital, Istanbul, Turkey.

The Turkish Journal of Pediatrics
|March 28, 2008
PubMed

Insights

Asthma severity, allergic rhinitis, and steroid use significantly impact children's quality of life (QOL). Lung function did not correlate with QOL in this pediatric asthma study.

Area of Science:

  • Pediatric Pulmonology
  • Quality of Life Research
  • Allergy and Immunology

Background:

  • Childhood asthma significantly affects daily life and well-being.
  • Understanding factors influencing quality of life (QOL) is crucial for effective management.
  • Pediatric asthma management requires a holistic approach beyond lung function.

Purpose of the Study:

  • To assess the quality of life (QOL) in children with asthma.
  • To identify key factors influencing QOL among pediatric asthma patients.
  • To establish a baseline for longitudinal monitoring of QOL in this population.

Main Methods:

  • Cross-sectional study involving 305 pediatric asthma outpatients (aged 7-17).
  • Quality of life assessed using the Pediatric Asthma QOL Questionnaire (PAQLQ).
  • Multivariate regression models used to analyze associations between clinical factors and PAQLQ scores.

Main Results:

  • Asthma severity, allergic rhinitis, and steroid usage were negatively associated with overall PAQLQ scores (p=0.038).
  • Lung function measures, while correlated with each other, showed no significant association with QOL (p=0.441).
  • 51% of pediatric patients reported significant life impact from asthma; other factors like IgE, skin tests, and smoking showed no significant effect.

Conclusions:

  • Asthma severity, allergic rhinitis, and steroid use are significant determinants of QOL in children with asthma.
  • Lung function is not a reliable indicator of QOL in this pediatric population.
  • Findings provide baseline data for future research and clinical interventions to improve pediatric asthma QOL.

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