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Published on: February 23, 2014
Community-acquired pneumonia and parapneumonic effusions in developing countries
Gülten Seçmeer1, Arbay O Ciftçi, Güler Kanra
1Department of Pediatrics, Hacettepe University Faculty of Medicine, Ankara, Turkey.
Abstract:
Ninety-eight patients with diagnosis of community-acquired pneumonia and parapneumonic effusion were retrospectively evaluated in order to determine the demographic properties of the patients, etiologic microorganism and the resistance patterns. Ages of study groups were between 2 to 16 years (mean 6.5 +/- 3.5 years) and 56 of 98 patients (56%) were male. There were four groups: Pneumonia (Group 1, n: 57), pleural effusion-medical treatment (Group 2, n: 18), pleural effusion-tube thoracostomy (Group 3, n: 19), and pleural effusion-operative treatment (Group 4, n: 4). Pre-admission antibiotic use was up to 84% in study groups. Evaluation of seasonal dispersion revealed that 86.7% of patients were admitted to hospital in the October-May period. Blood cultures were positive in 4 of 98 patients (4%). Nine of 27 (33.3%) pleural effusion cultures were positive and 4 of them revealed Streptococcus pneumoniae. Intermediate penicillin resistance was found in 1/4 of S. pneumoniae isolates (25%). Our study illustrates the problems in the diagnosis and management of pediatric respiratory tract infections in developing countries. Chest X-ray together with erythrocyte sedimentation rate (ESR) was also shown to be important in classifying lower respiratory tract infections. Increase in the usage of specific viral serologic studies will probably lower the percentage of antibiotic usage and lower the costs of cultures.
Insights
Community-acquired pneumonia in children is common, especially in colder months. Streptococcus pneumoniae was a key pathogen, with some penicillin resistance, highlighting challenges in developing countries.
Area of Science:
- Pediatrics
- Infectious Diseases
- Respiratory Medicine
Background:
- Community-acquired pneumonia (CAP) and parapneumonic effusion are significant pediatric respiratory infections.
- Management challenges exist, particularly in developing countries, with high rates of pre-admission antibiotic use.
Purpose of the Study:
- To determine demographic properties, etiologic microorganisms, and resistance patterns in pediatric CAP with parapneumonic effusion.
- To evaluate diagnostic and management strategies for these infections.
Main Methods:
- Retrospective evaluation of 98 pediatric patients diagnosed with CAP and parapneumonic effusion.
- Analysis of patient demographics, seasonal distribution, microbial cultures (blood and pleural fluid), and antibiotic resistance patterns.
Main Results:
- The study included 98 patients (mean age 6.5 years, 56% male).
- Streptococcus pneumoniae was identified in 4 of 27 positive pleural effusion cultures, with 25% intermediate penicillin resistance.
- High pre-admission antibiotic use (84%) and seasonal clustering (October-May) were observed.
Conclusions:
- Pediatric respiratory tract infections pose diagnostic and management challenges in developing nations.
- Chest X-ray and erythrocyte sedimentation rate (ESR) aid in classifying lower respiratory tract infections.
- Increased use of viral serologic studies could reduce antibiotic usage and costs.
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