Related Experiment Video
Updated: Jul 6, 2026

Mouse Models of Epididymitis Induced by Pathogen-Associated Molecular Patterns
Published on: December 12, 2025
A child with Behçet's disease presenting with a spectrum of inflammatory manifestations including epididymoorchitis
Ayhan Pektaş1, Ilker Devrim, Nesrin Beşbaş
1Department of Pediatrics, Hacettepe University Faculty of Medicine, Ankara, Turkey.
Insights
This study details an 11-year-old with Behçet's disease, a rare systemic vasculitis. The patient experienced unusual symptoms including myositis, epididymoorchitis, fever, and thrombophlebitis.
Area of Science:
- Rheumatology
- Pediatrics
- Vasculitis
Background:
- Behçet's disease is a systemic vasculitis affecting small blood vessels.
- It typically presents with oral ulcers, genital ulcers, and ocular inflammation.
- Commonly affects joints, skin, CNS, and GI tract.
Observation:
- An 11-year-old patient with Behçet's disease is presented.
- The patient experienced recurrent myositis (muscle inflammation) and epididymoorchitis (inflammation of the epididymis and testes).
- Additional symptoms included periodic fever attacks and a separate thrombophlebitis (vein inflammation) event.
Findings:
- This case highlights unusual manifestations of Behçet's disease in a pediatric patient.
- The co-occurrence of myositis, epididymoorchitis, and thrombophlebitis is noteworthy.
- Periodic fever attacks were also a significant clinical feature.
Implications:
- This case expands the understanding of Behçet's disease presentations in children.
- It underscores the importance of considering vasculitis in pediatric patients with complex inflammatory symptoms.
- Further research may elucidate the specific mechanisms driving these diverse manifestations.
Abstract:
Behçet's disease is a systemic vasculitis affecting arterioles and venules and is characterized by recurrent oral ulcers, genital ulcers and ocular inflammation. It can involve any organ but joints, skin, central nervous system and gastrointestinal tract are the most common sites. Here we report an 11-year-old Behçet's disease patient presenting with attacks of myositis accompanied by epididymoorchitis and periodic fever attacks as well as a separate attack of thrombophlebitis.
Related Concept Videos
Inflammatory Bowel Disease II: Crohn's Disease
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by transmural...
Chronic Bowel Disorders: Introduction
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
Inflammatory Bowel Disease III: Crohn's Disease
Inflammatory Bowel Disease IV: Clinical Manifestations
Amebiasis
Endocarditis II: Clinical Features of Infective Endocarditis
