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Is a flared stent effective for decreasing stent migration in canine prostatic urethra?
Chul-Woong Woo1, Ho-Young Song, Chang Jin Yoon
1Department of Radiology and Research Institute of Radiology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Republic of Korea.
Acta Radiologica (Stockholm, Sweden : 1987)
|March 28, 2008
Summary
Flared prostatic urethral stents showed a trend towards reduced migration compared to straight stents in dogs. However, migration rates remained high, necessitating further innovation for improved stent stability.
Area of Science:
- Urology
- Biomedical Engineering
- Veterinary Medicine
Background:
- Prostatic urethral stents are used to treat benign prostatic hyperplasia (BPH) obstructions.
- Stent migration is a common complication, leading to reduced efficacy.
Purpose of the Study:
- To compare the migration rates of flared versus straight prostatic urethral stents.
- To evaluate the efficacy of stent flaring in preventing migration in a canine model.
Main Methods:
- Flared and straight nitinol stents coated with ePTFE were implanted in canine prostates.
- Migration was assessed via retrograde urethrography at 1, 4, and 8 weeks.
- Fisher's exact test analyzed migration rate differences.
Main Results:
- 30% of flared stents and 58.3% of straight stents migrated.
- The flared stent group exhibited a lower, though not statistically significant, migration rate (P=0.231).
- Re-implanted flared stents also showed a high migration rate (33.3%).
Conclusions:
- Stent flaring may offer a modest reduction in migration compared to straight designs.
- Current flared stent designs still exhibit significant migration issues.
- Further research and development are needed to improve prostatic stent stability.
