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Related Experiment Video

Updated: Jul 6, 2026

Surgical Porcine Model of Chronic Myocardial Ischemia Treated by Exosome-laden Collagen Patch and Off-pump Coronary Artery Bypass Graft

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Does off-pump coronary surgery endanger long term survival?

Rolf Ekroth, Anders Odén, Elisabeth Ståhle

Scandinavian Cardiovascular Journal : SCJ

|March 28, 2008

Summary

Off-pump coronary artery bypass surgery poses technical hazards, with higher rates of under-grafting and graft failure compared to standard operations. Further research is needed before widespread adoption, suggesting a temporary halt in its use.

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Evaluation of a Novel Laser-assisted Coronary Anastomotic Connector - the Trinity Clip - in a Porcine Off-pump Bypass Model

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Published on: November 24, 2014

Area of Science:

Cardiovascular Surgery
Surgical Innovation
Evidence-Based Medicine

Background:

Off-pump coronary artery bypass (OPCAB) surgery aims to avoid cardiopulmonary bypass.
Technical challenges and potential complications of OPCAB are under investigation.
Existing meta-analyses of randomized trials provide comparative data on OPCAB outcomes.

Discussion:

Ibrahim and co-authors highlight significant technical hazards associated with OPCAB surgery.
Findings indicate a higher incidence of under-grafting and graft failure in OPCAB compared to conventional coronary artery bypass grafting.
The study critically examines the implications of these findings for achieving surgical objectives.

Key Insights:

Off-pump surgery is associated with increased risks of graft failure and under-grafting.
Evidence suggests OPCAB may compromise the long-term success of coronary bypass surgery.
A cautious approach is warranted due to current data limitations.

Outlook:

A moratorium on off-pump coronary surgery is proposed pending conclusive evidence.
Further high-quality randomized trials are necessary to clarify the safety and efficacy of OPCAB.
Future research should focus on mitigating technical risks and improving long-term graft patency.