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Long-term follow-up of patients treated with ICD: benefit in patients with preserved left ventricular function

Folke Rönn1, Milos Kesek, Niklas Höglund

  • 1Department of Cardiology, Heart Centre, Umeå University Hospital, Sweden.

Scandinavian Cardiovascular Journal : SCJ
|March 28, 2008
PubMed

Insights

Implantable cardioverter-defibrillators (ICDs) benefit patients with preserved heart function, offering life-saving therapy and good quality of life. Long-term outcomes show substantial survival benefits and low mortality in this population.

Area of Science:

  • Cardiology
  • Medical Devices
  • Clinical Trials

Background:

  • Major defibrillator trials often have limited follow-up periods.
  • This limits understanding of long-term benefits in patients with preserved ejection fraction and advanced heart disease progression.

Purpose of the Study:

  • To investigate the long-term outcomes of implantable cardioverter-defibrillators (ICDs) in an unselected patient population.
  • To evaluate the effectiveness and safety of ICDs over an extended follow-up period.

Main Methods:

  • A cohort of 124 consecutive patients receiving an ICD between 1993-2002 was followed for a median of 6.1 years.
  • Data on heart disease, index arrhythmia, follow-up, and mortality were retrospectively collected from medical records.

Main Results:

  • Crude mortality was 26% over the follow-up period.
  • Heart failure was the primary cause of death (75%), particularly in patients with ejection fraction <35% (91% of deaths).
  • An estimated 28% of patients received life-saving ICD therapy, with no significant relation between saved lives/complications and ejection fraction.

Conclusions:

  • Implantable cardioverter-defibrillators (ICDs) are highly beneficial for patients with preserved left ventricular function.
  • These patients experience substantial life-saving therapies, low mortality rates, and maintain a good quality of life.
Abstract

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