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Related Experiment Video

Updated: Jul 6, 2026

Use of Magnetic Resonance Imaging and Biopsy Data to Guide Sampling Procedures for Prostate Cancer Biobanking
05:49

Use of Magnetic Resonance Imaging and Biopsy Data to Guide Sampling Procedures for Prostate Cancer Biobanking

Published on: October 10, 2019

Tissue-marking scheme for a cost-effective extended prostate biopsy protocol.

Farzeen Firoozi1, Tipu Nazeer, Hugh A G Fisher

  • 1Division of Urology, Albany Medical College, Albany, NY 12208, USA.

Urologic Oncology
|March 28, 2008
PubMed
Summary

A new protocol for prostate biopsies bundles tissue samples, reducing pathology costs without losing crucial prognostic data. This method ensures efficient prostate cancer detection and management.

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Area of Science:

  • Urology
  • Pathology
  • Health Economics

Background:

  • Extended prostate biopsy schemes are standard for cancer detection.
  • Individual core submission increases pathology costs and can obscure prognostic information.
  • Bundling biopsy cores presents a challenge in balancing cost-effectiveness with diagnostic accuracy.

Purpose of the Study:

  • To develop and evaluate a protocol for bundling prostate biopsy cores.
  • To reduce the cost of pathologic evaluation while preserving essential prognostic information.
  • To maintain the ability to identify important biopsy features within bundled samples.

Main Methods:

  • A prospective protocol involving 452 men undergoing prostate biopsy.
  • Lateral peripheral cores marked with India ink and combined with sextant site cores (max 6 containers).

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Enhancing Prostate Tumor Biobanking Reliability with Improved Sampling Technique and Histological Characterization
07:34

Enhancing Prostate Tumor Biobanking Reliability with Improved Sampling Technique and Histological Characterization

Published on: November 17, 2023

Related Experiment Videos

Last Updated: Jul 6, 2026

Use of Magnetic Resonance Imaging and Biopsy Data to Guide Sampling Procedures for Prostate Cancer Biobanking
05:49

Use of Magnetic Resonance Imaging and Biopsy Data to Guide Sampling Procedures for Prostate Cancer Biobanking

Published on: October 10, 2019

Enhancing Prostate Tumor Biobanking Reliability with Improved Sampling Technique and Histological Characterization
07:34

Enhancing Prostate Tumor Biobanking Reliability with Improved Sampling Technique and Histological Characterization

Published on: November 17, 2023

  • Prognostic information recorded per core; cost analysis based on container numbers.

    • Main Results:

    • The tissue-labeling protocol caused no artifacts or increased procedure time.
    • Cancer detected in 39% of men (mean Gleason score 7).
    • Significant cost savings achieved by reducing containers, with potential for millions in annual savings.

    Conclusions:

    • A simple tissue-labeling protocol enables cost-effective extended prostate biopsies.
    • Important prognostic information from each core is maintained.
    • This approach supports efficient prostate cancer detection and management.