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Updated: Jul 6, 2026

Home-Based Prescribed Pulmonary Exercise in Patients with Stable Chronic Obstructive Pulmonary Disease
Published on: August 24, 2019
The Severe Respiratory Insufficiency Questionnaire was valid for COPD patients with severe chronic respiratory
Wolfram Windisch1, Stephan Budweiser, Frank Heinemann
1Department of Pneumology, University Hospital Freiburg, Killianstrasse 5, D-79106 Freiburg, Germany. wolfram.windisch@uniklinik-freiburg.de
Objectives:
The Severe Respiratory Insufficiency (SRI) Questionnaire has recently been developed and validated for the assessment of health-related quality of life (HRQL) in patients with severe chronic respiratory failure resulting from a broad spectrum of underlying disorders. The present study was aimed at reexamining the internal structure of the SRI specifically for chronic obstructive pulmonary disease (COPD) patients.
Study Design And Setting:
Cross-validation was performed in two COPD groups (N=78 and N=84), each receiving home mechanical ventilation in addition to long-term oxygen therapy. The internal consistency reliability was calculated using Cronbach's alpha coefficient. Explorative Factor Analysis was performed followed by Confirmatory Factor Analysis to establish construct validity.
Results:
In the total group (N=162) Cronbach's alpha ranged from 0.73 to 0.88. Only one factor could be established which explained 58.5% of the total variance confirming one Summary Scale (SRI-SS). For each of the seven subscales, Confirmatory Factor Analysis revealed two factors, which were substantially correlated (r=0.43-0.80). All scale scores covered a broad range of the questionnaire's scaling range (0-100). The mean SRI-SS score was 52+/-17 indicating a homogenous scaling distribution.
Conclusion:
The SRI is a multidimensional and highly specific tool with high psychometric properties for HRQL assessment in COPD patients with severe chronic respiratory failure.
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