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Published on: March 26, 2019
[Analysis of subdural intracraneal empyemas in a third level hospital]
M A Hernández-Hernández1, M A Ballesteros-Sanz, M Gutiérrez-Cuadra
1Servicio de Medicina Intensiva, Hospital Universitario Marqués de Valdecilla, Avda, Valdecilla, s/n, E-39008 Santander (Cantabria), España. mahernandez@humv.es
Introduction:
Intracranial subdural empyema (ISE) is an infrequent infectious disorder of diverse etiology and difficult to diagnose because of its non-specific clinical features.
Patients And Methods:
Retrospective study of patients diagnosed of ISE in a third-level university hospital in a 15-year period.
Results:
Five men were included (mean age: 39.3 years). The most frequent primary source of infection was otic and sinusal (60%). The initial clinical manifestations were fever, headache, alteration of consciousness, and neurological focal symptoms. The mean time elapsed between onset of symptoms and diagnosis was 3.6 days. Diagnosis was performed by computed tomography in all patients. ISE was localized in the left hemisphere in 60% of cases mainly affecting the parietal lobe (80%). Anaerobic and streptococci germs were the most frequently isolated microorganisms. Therapy was based on antibiotics and surgical drainage in 100% of the cases. The surgical procedure used in the evacuation of empyema was craniotomy in all the patients. The mean time elapsed between diagnosis and surgery was 8.4 days. The mean Intensive Care Unit stay was 12.8 days, whereas the overall mean in-hospital stay was 45.2 days. Mortality was 40%.
Conclusion:
ISE, although infrequent, displays a high morbimortality that can be reduced with an early therapeutic approach which may include the surgical evacuation in all the cases.
Insights
Intracranial subdural empyema (ISE) is a rare but serious infection. Early diagnosis and surgical intervention are crucial for reducing high mortality rates in patients with this condition.
Area of Science:
- Neurology
- Infectious Diseases
- Neurosurgery
Context:
- Intracranial subdural empyema (ISE) presents with non-specific symptoms, complicating early diagnosis.
- This retrospective study analyzes a 15-year period of ISE cases at a tertiary university hospital.
Purpose:
- To investigate the clinical features, diagnosis, treatment, and outcomes of intracranial subdural empyema.
- To highlight the importance of timely therapeutic approaches in managing ISE.
Summary:
- The study included five male patients with ISE, predominantly originating from otic and sinusal infections.
- Diagnosis via CT scan revealed left-hemisphere localization in most cases. Treatment involved antibiotics and craniotomy for surgical drainage.
- High morbimortality (40%) was observed, emphasizing the need for prompt intervention.
Impact:
- Findings underscore the critical role of early diagnosis and surgical evacuation in improving outcomes for intracranial subdural empyema.
- This research contributes to understanding the management of a rare but severe neurological infection.
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