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Updated: Jul 6, 2026

A Protocol for Roux-en-Y Gastric Bypass in Rats using Linear Staplers
Published on: August 21, 2021
Advances in circular stapling technique for gastric bypass: transoral placement of the anvil
Ninh T Nguyen1, Marcelo W Hinojosa, Brian R Smith
1Department of Surgery, University of California Irvine Medical Center, 333 City Bldg. West, Suite 850, Orange, CA, USA. ninhn@uci.edu
Abstract:
In Roux-en-Y gastric bypass, construction of the gastrojejunostomy is commonly performed using a circular stapler. The initial description for placement of the anvil was via the transoral approach. Although the concept was ingenious, technical difficulty was encountered during passage resulting in complications such as hypopharyngeal perforation and esophageal mucosal injury. As a result, most surgeons subsequently changed their route of anvil placement to the transabdominal approach. Advances in stapler technology now allow the head of the anvil to be pre-tilted, permitting transoral introduction with greater ease and safety. This paper describes this improved method for transoral placement of the anvil during laparoscopic gastric bypass and reoperative bariatric surgery.
