An electro-fluid-dynamic simulator for the cardiovascular system
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Updated: Mar 27, 2026

In Silico Clinical Trials for Cardiovascular Disease
Published on: May 27, 2022
Celso Luiz Felipini1, Aron José Pazin de Andrade, Júlio César Lucchi
1University Sao Judas Tadeu, São Paulo, SP, Brazil. aandrade@fajbio.com.br
Abstract:
This work presents the initial studies and the proposal for a cardiovascular system electro-fluid-dynamic simulator to be applied in the development of left ventricular assist devices (LVADs). The simulator, which is being developed at University Sao Judas Tadeu and at Institute Dante Pazzanese of Cardiology, is composed of three modules: (i) an electrical analog model of the cardiovascular system operating in the PSpice electrical simulator environment; (ii) an electronic controller, based on laboratory virtual instrumentation engineering workbench (LabVIEW) acquisition and control tool, which will act over the physical simulator; and (iii) the physical simulator: a fluid-dynamic equipment composed of pneumatic actuators and compliance tubes for the simulation of active cardiac chambers and big vessels. The physical simulator (iii) is based on results obtained from the electrical analog model (i) and physiological parameters.

