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Updated: Jul 6, 2026

A Culture Method to Maintain Quiescent Human Hematopoietic Stem Cells
Published on: May 17, 2021
Stem cells and the rate of living
Janakiraman Krishnamurthy1, Norman E Sharpless1
1Departments of Medicine and Genetics, The Lineberger Comprehensive Cancer Center, The University of North Carolina School of Medicine, Chapel Hill, NC 27599, USA.
Abstract:
The "rate-of-living theory" is an ancient explanation of longevity which holds that aging occurs due to the exhaustion of some finite substance-breaths, heartbeats, etc. While this theory as originally conceived has been debunked, new work (Ruzankina et al. [2007], in this issue of Cell Stem Cell) suggests that mammals in fact do have a finite number of stem cell replications per life.
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