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Updated: Jul 6, 2026

Dynamic Electrochemical Measurement of Chloride Ions
Published on: February 5, 2016
Determination of chloride, chlorate and perchlorate by PDMS microchip electrophoresis with indirect amperometric
Xin-Ai Li1, Dong-Mei Zhou, Jing-Juan Xu
1Key Lab of Analytical Chemistry for Life Sciences (MOE), School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210093, China.
Abstract:
In this work, chloride, chlorate and perchlorate are fast separated on PDMS microchip and detected via in-channel indirect amperometric detection mode. With PDMS/PDMS microchip treated by oxygen plasma, anions chloride (Cl-), chlorate (ClO3-), and perchlorate (ClO4-) are separated within 35s. Some parameters including buffer salt concentration, buffer pH, separation voltage and detection potential are investigated in detail. The separation conditions using 15 mM (pH 6.12) of 2-(N-morpholino)ethanesulfonic acid (MES)+L-histidine (L-His) as running buffer, -2000 V as separation voltage and 0.7 V as detection potential are optimized. Under this condition, the detection limits of Cl-, ClO3-, and ClO4- are 1.9, 3.6, and 2.8 microM, respectively.
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