Related Experiment Video
Updated: Jul 6, 2026

13:44
Detection of Architectural Distortion in Prior Mammograms via Analysis of Oriented Patterns
Published on: August 30, 2013
A step toward computer-assisted mammography using evolutionary programming and neural networks
D B Fogel1, E C Wasson, E M Boughton
1Natural Selection, Inc., 3333 N. Torrey Pines Ct., Suite 200, La Jolla, CA 92037, USA. dfogel@natural-selection.com
Cancer Letters
|April 1, 2008
Summary
Artificial intelligence (AI) can enhance breast cancer detection by providing a second opinion. Evolutionary programming trained neural networks show promise in identifying malignancies from radiographic data.
Area of Science:
- Medical imaging analysis
- Artificial intelligence in healthcare
- Oncology diagnostics
Background:
- Artificial intelligence (AI) offers potential for improving diagnostic accuracy and cost-effectiveness in medicine.
- AI can serve as a valuable tool for second opinions in clinical settings.
- Early and accurate breast cancer detection is crucial for patient outcomes.
Purpose of the Study:
- To investigate the efficacy of artificial neural networks (ANNs) trained with evolutionary programming for breast cancer detection.
- To evaluate the use of radiographic features and patient age in AI-driven cancer diagnosis.
- To assess the diagnostic performance of simple neural architectures in identifying malignant breast masses.
Main Methods:
- Utilized evolutionary programming to train artificial neural networks (ANNs).
- Employed radiographic features and patient age as input data for the models.
- Analyzed data from 112 biopsy-proven breast masses (63 malignant, 49 benign).
Main Results:
- The trained ANNs demonstrated a significant probability of detecting malignancies.
- Simple neural architectures were sufficient for achieving high detection rates.
- A small percentage of false positives were observed in the diagnostic results.
Conclusions:
- AI techniques, specifically evolutionary programming-trained ANNs, show potential for accurate breast cancer detection.
- The study highlights the feasibility of using AI for improving diagnostic sensitivity and specificity in mammography.
- Further research into refining AI models can minimize false positives and enhance clinical utility.
