Related Experiment Video
Updated: Jul 6, 2026

Homogeneous Time-resolved Förster Resonance Energy Transfer-based Assay for Detection of Insulin Secretion
Published on: May 10, 2018
[Brazilian Consensus on second-generation antipsychotics and metabolic disorders]
Helio Elkis1, Clarissa Gama, Henrique Suplicy
1Instituto de Psiquiatria, Universidade de São Paulo, São Paulo, SP, Brasil. helkis@usp.br
Objective:
To discuss current aspects of use of antipsychotics considering their metabolic side effects profile, which includes weight gain, dyslipidemias, diabetes and metabolic syndrome. Such metabolic effects increase the risk of mortality by cardiovascular disease, which is the leading cause of death among schizophrenic patients.
Method:
A consensus meeting was held, with participation of endocrinologists and psychiatrists specialists in schizophrenia and, based on a literature review, an article was elaborated emphasizing practical and helpful recommendations to clinicians.
Results And Conclusions:
Monitoring metabolic side effects is essential to patients taking antipsychotics, particularly in the case of second generation antipsychotics. Efficacy and tolerability should be carefully balanced in all phases of treatment.
Related Concept Videos
Antipsychotic Drugs: Typical and Atypical Agents
Drug Therapy
Antianxiety Medications
Psychosis: Goals of Pharmacotherapy
Psychosis and Antipsychotic Drugs: Overview
Oral Hypoglycemic Agents: Biguanides and Glitazones
Antipsychotic Drugs: Therapeutic Uses and Side Effects
Despite these side effects, antipsychotics are used therapeutically for various purposes, including managing schizophrenia, preventing nausea and vomiting, curbing...
