Related Experiment Video
Updated: Jul 6, 2026

A Computational Modeling Approach to Investigate the Influence of Hyperthermia on the Tumor Microenvironment
Published on: December 1, 2023
Key issues in bioheat transfer simulations for the application of cryosurgery planning
1Biothermal Technology Laboratory, Department of Mechanical Engineering, Carnegie Mellon University, 5000 Forbes Avenue, Pittsburgh, PA 15237, USA. rabin@cmu.edu
Abstract:
The bioheat transfer simulation is undoubtedly the foundation for developing computerized tools for cryosurgery planning and analysis. While a large variety of techniques for bioheat transfer simulations are available in the literature of the past several decades, it is only their integration with clinical criteria and constraints which can make computerized planning a practical reality. This brief communication outlines (in the opinion of this author) the key issues that must be addressed in the application of bioheat transfer to cryosurgery planning and analysis, while drawing attention to recent and relevant publications in other journals, with reference to the most recent publication on the topic in the Journal of Cryobiology [Z. Magalov, A. Shitzer, D. Degani, Isothermal volume contours generated in a freezing gel by embedded cryo-needles with applications to cryo-surgery, Cryobiology 55 (2) (2007) 127-137].
Related Concept Videos
Mechanisms of Heat Transfer II
Mechanisms of Heat Transfer I
Mechanisms of Heat Transfer
Conduction, accounting for approximately 3% of body heat loss at rest, is the process of exchanging heat between molecules of two materials in direct contact. This can result in both heat loss and gain. For instance, when the body is submerged in water, which conducts heat 20 times more effectively than air, it can either lose or gain significant heat.
Mechanism of heat transfer
Conduction, Convection and Radiation: Problem Solving
In order to solve a problem related to heat transfer, first of all, the situation needs to be examined to determine the type of heat transfer involved. This could...

