Related Experiment Video
Updated: Jul 6, 2026

An Immunohistopathologic Study to Profile the Folate Receptor Beta Macrophage and Vascular Immune Microenvironment in Giant Cell Arteritis
Published on: February 8, 2019
[Wegener's granulomatosis with clinical manifestations of temporal arteritis]
L Astudillo1, G Pugnet, F Bidegain
1Service de médecine interne, centre hospitalier universitaire de Purpan, Toulouse cedex, France. astudillo.1@chu-toulouse.fr
Abstract:
A 51-year-old woman presented with crusting rhinitis, bilateral serous otitis, inflammatory arthralgias, fever, weight loss and signs of temporal arteritis. Temporal arteries were increased in size, painful, with inflammatory signs. There was microscopic hematuria and inflammatory parameters were increased. The renal function was normal. Anticytoplasmic neutrophils antibodies were detected (anti-PR3). Temporal artery biopsy did not show signs of giant cell arteritis. A diagnostic of Wegener's granulomatosis was established and steroid treatment allowed disappearance of clinical and biologic features.
Related Concept Videos
Graves' Disease I: Introduction
Endocarditis II: Clinical Features of Infective Endocarditis
Chronic Inflammation: Introduction
Graves Disease II: Pathophysiology
Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies
Asthma III: Clinical Manifestations