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Updated: Jul 6, 2026
07:45
Orthotopic Transplantation of Breast Tumors as Preclinical Models for Breast Cancer
Published on: May 18, 2020
Translational research in breast cancer
Quyen D Chu1, Neal Holm, Kerry Byrnes
1Department of Surgery, Louisiana State University Health Sciences Center-Shreveport, The Feist-Weiller Cancer Center, 1501 Kings Highway, P.O. Box 33932, Shreveport, LA 71130-3932, USA. qchu@lsuhsc.edu
Surgical Oncology Clinics of North America
|April 1, 2008
Summary
The Human Genome Project identified 25,000 human genes, revolutionizing disease research. This genetic insight has transformed breast cancer treatment from population risk to molecular classification.
Area of Science:
- Genomics
- Molecular Biology
- Oncology
Background:
- The Human Genome Project identified approximately 25,000 human genes.
- Understanding gene function is crucial for disease research.
- Breast cancer research has significantly benefited from genomic discoveries.
Purpose of the Study:
- To highlight the impact of the Human Genome Project on understanding human diseases.
- To emphasize the shift in breast cancer treatment paradigms.
- To discuss the transition towards molecular classification in oncology.
Main Methods:
- Review of genomic data and its application in disease research.
- Analysis of molecular techniques in cancer diagnostics.
- Comparative study of traditional vs. molecular-based treatment models.
Main Results:
- The Human Genome Project provided a comprehensive map of human genes.
- Molecular-level understanding has deepened insights into cancer development.
- Novel molecular techniques enable precise disease classification.
Conclusions:
- Genomic discoveries have profoundly impacted translational medicine.
- Breast cancer treatment is increasingly driven by molecular profiling.
- Molecular classification represents a paradigm shift in personalized oncology.
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