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Updated: Jul 6, 2026

A Machine Learning Approach to Design an Efficient Selective Screening of Mild Cognitive Impairment
Published on: January 11, 2020
Primary care screening for cognitive impairment in elderly veterans
Kerry Donnelly1, James P Donnelly, Elizabeth Cory
1Veterans Affairs Western New York Healthcare System, Bufallo, NY 14215, USA. kerry.donnelly@va.gov
Primary care screening for cognitive impairment in elderly veterans proved ineffective. Brief standardized tests like the Mini-Mental State Exam and Trail Making Test (TMT)-B showed better diagnostic accuracy.
Area of Science:
- Gerontology
- Neuropsychology
- Primary Care Medicine
Background:
- Cognitive impairment is a significant concern in elderly populations, particularly veterans.
- Accurate and efficient screening tools are crucial for early detection and intervention in primary care settings.
Purpose of the Study:
- To evaluate the diagnostic accuracy of a primary care screening procedure for cognitive impairment in elderly veterans.
- To compare its performance against four standardized brief neuropsychological tests.
Main Methods:
- A study involving 100 primary care patients (elderly veterans) requiring cognitive impairment screening.
- Comparison of an existing interview-based screening procedure with the Mini-Mental State Exam, Clock Drawing Test, and Trail Making Test (TMT)-A and TMT-B.
Main Results:
- The existing primary care screening procedure failed to identify any cases of cognitive impairment.
- Mini-Mental State Exam, Clock Drawing Test, and TMT-A/TMT-B demonstrated approximately 80% correct classification rates.
- Trail Making Test B (TMT-B), with a cutoff of 3 minutes, showed strong predictive validity across multiple indicators.
Conclusions:
- The current interview-based screening procedure lacks diagnostic accuracy for cognitive impairment in this population.
- Brief, standardized neuropsychological tests, particularly TMT-B, are more effective screening tools.
- Further research into brief, standardized screening methods is recommended for elderly veterans.
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