Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Micro-engineered remote palpation device for assessing tissue compliance.

M Hien1, T H J Yang, S K W Leung

  • 1Heriot-Watt University, School of Engineering and Physical Sciences, Edinburgh, UK. mrh6@hw.ac.uk

Studies in Health Technology and Informatics
|April 1, 2008
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Microcell-mediated transfer of chromosome 4 into HeLa cells suppresses telomerase activity.

Genes, chromosomes & cancer·2001
Same author

Fabrication of a single-appointment emergency overdenture using failed fixed prosthetics: a case report.

Implant dentistry·2001
Same author

Quality of life after treatment for early laryngeal carcinoma.

European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·2001
Same author

HPV16 L1E7 chimeric virus-like particles induce specific HLA-restricted T cells in humans after in vitro vaccination.

International journal of cancer·2001
Same author

Endoscopic axillary lymphadenectomy without prior liposuction in 100 patients with invasive breast cancer.

Surgical laparoscopy, endoscopy & percutaneous techniques·2001
Same author

The application of fetal magnetocardiography (FMCG) to investigate fetal arrhythmias and congenital heart defects (CHD).

Prenatal diagnosis·2001
Same journal

A GenAI Pipeline for Violinist Kinematic Data Management.

Studies in health technology and informatics·2026
Same journal

AMAL-For-Qatar: A Comprehensive AI Ecosystem for Fetal Ultrasound Analysis - Project Overview and Achievements.

Studies in health technology and informatics·2026
Same journal

Longitudinal Treatment-Aware Multimodal AI for Dermatology: A Scoping Review.

Studies in health technology and informatics·2026
Same journal

Predicting Postpartum Depression Using Imbalance-Aware Machine Learning.

Studies in health technology and informatics·2026
Same journal

Validation of Deep-Learning Models for Autosegmentation of Brain Metastases.

Studies in health technology and informatics·2026
Same journal

Delay-Dependent Gating in Modular RNNs.

Studies in health technology and informatics·2026
See all related articles

This study assesses a micro-engineered actuator for prostate mechanical property measurement. The device utilizes a silicon micro-piston and a programmable pump to evaluate tissue in vivo.

Area of Science:

  • Biomedical Engineering
  • Mechanical Engineering
  • Materials Science

Background:

  • Prostate cancer diagnosis and monitoring require accurate assessment of tissue mechanical properties.
  • Existing methods for in vivo mechanical property measurement are limited in precision and scope.
  • Micro-engineered devices offer potential for minimally invasive and high-resolution palpation.

Purpose of the Study:

  • To evaluate the operational functionality of a novel micro-engineered actuator assembly.
  • To validate the actuator's capability for measuring dynamic mechanical properties of the prostate gland in vivo.
  • To assess the performance of the micro-piston and associated components within the palpation device.

Main Methods:

  • Fabrication of a micro-actuator using deep reactive ion etching (DRIE) for a silicon piston.

Related Experiment Videos

  • Assembly of the micro-piston within a glass-Si-glass housing with a silicone membrane seal.
  • Integration of a micro-syringe pump and pressure sensor for controlled reciprocating motion and dynamic pressure measurement.
  • Utilizing powder blasting for micro-channel creation and capillary tubing for fluidic connection.

    • Main Results:

    • The micro-piston and actuator assembly were successfully fabricated and integrated.
    • The system demonstrated controlled reciprocating action via the programmable syringe pump.
    • The pressure sensor effectively measured dynamic pressure changes within the micro-channel.
    • Preliminary tests confirmed the micro-piston's capability to actuate and measure mechanical properties.

    Conclusions:

    • The developed micro-engineered actuator assembly is functional for its intended purpose.
    • The device shows promise for in vivo measurement of prostate dynamic mechanical properties.
    • Further validation and clinical deployment are warranted for this micro-palpation technology.