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Rhinocerebral mucormycosis in a child with acute lymphoblastic leukemia: a case report
Gheorghe Popa1, Cristina Blag, Florina Sasca
1Department of Pediatric Oncology, Pediatric Clinic No 2, University of Medicine and Pharmacy, Iuliu Hatieganu Cluj-Napoca, Romania. ghitapopa2000@yahoo.com
Background:
Mucormycosis is a life-threatening fungal infection in patients with predisposing conditions.
Case Report:
We report the case of a 7-year-old girl with acute lymphoblastic leukemia and rhinocerebral mucormycosis who successfully completed chemotherapy. The infection with Rhizopus genus was mycologically identified from nasal secretions and therapy was based on amphotericin B with surgical debridement. Chemotherapy was safely continued after resolution of the mycosis and the patient remains in continuous complete remission at 30 months.
Conclusions:
Rhinocerebral mucormycosis in acute lymphoblastic leukemia is manageable with sequential therapy including, amphotericin B, surgery, and risk-adapted chemotherapy.
